A single bald patch on the scalp can happen due to conditions like alopecia areata, fungal infection, or localised inflammation, and the treatment usually depends on the exact cause identified by your doctor. The medicines you mentioned are commonly used in hair-related problems and are generally considered safe when used as prescribed, since they work in different ways rather than interfering with each other. MX 5% solution (minoxidil) helps stimulate hair follicles and improve regrowth over time, while vitamin A, E, and D supplements support overall nutritional balance that can affect hair health. Ketomac shampoo helps control dandruff or fungal involvement, which can sometimes worsen hair fall. Emersons cream may be used for local scalp inflammation or infection, depending on the diagnosis. Hair regrowth in a bald patch usually takes time, often several weeks to months, and consistent use is important. It is also normal to see slow improvement initially before visible regrowth appears. If the patch is increasing, new patches appear, or there is no response after a few months, follow-up with your doctor is important to reassess the condition and adjust treatment if needed.