Fever with headache, chills, and throat infection is most often due to a viral infection like the flu or sometimes a bacterial throat infection. These infections can cause body aches, weakness, and throat pain along with fever. Chills usually happen when your body temperature is rising. Treatment depends on the cause. Medicines to reduce fever and throat pain or antibiotics (if it is bacterial) may be used, but they should be taken only if advised by your doctor after proper evaluation. Taking antibiotics on your own is not recommended, as many throat infections are viral and improve without them. You can feel better with simple care. Take rest, drink plenty of warm fluids, and do saltwater gargles to soothe the throat. Steam inhalation can help if there is congestion. Eat light, soft foods and avoid cold items. If the fever is high, lasts more than a few days, or you have severe throat pain or difficulty swallowing, it is important to consult a doctor for proper treatment.