The numbness and tightness in your middle finger at night suggest potential nerve compression, such as Carpal Tunnel Syndrome, rather than a direct side effect of Nortryptomer P. You should not start any new medication or stop taking Nortryptomer P without consulting your doctor first. For immediate, drug-free relief at night, try wearing a neutral wrist splint to keep your joint straight while sleeping. Please consult your prescribing physician to evaluate these symptoms. They can determine the exact cause and safely prescribe appropriate anti-inflammatory or nerve-relieving medications if needed.