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  5. I have been suffering from internal itching for 9 years. I have tried medications like Levocetirizine, Cetirizine, Nucort M4, Kenacort injections, and Hydroxyzine, but they only provide temporary relief and the itching returns after 5 days. What alternative medicines should I take for long-lasting relief?

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I have been suffering from internal itching for 9 years. I have tried medications like Levocetirizine, Cetirizine, Nucort M4, Kenacort injections, and Hydroxyzine, but they only provide temporary relief and the itching returns after 5 days. What alternative medicines should I take for long-lasting relief?

Asked by Female, 45 · 4 days ago

Since antihistamines and steroids only provide temporary relief for your 9-year chronic itching, we must target the underlying cause, which may be neuropathic or systemic. For long-term relief, alternative prescription options include neuromodulators like Gabapentin or Pregabalin, which quiet overactive itch-sensing nerves. Other effective alternatives include tricyclic agents like Doxepin or opioid antagonists like Naltrexone. I highly recommend consulting a dermatologist or allergist to run comprehensive blood tests (checking kidney, liver, and thyroid function). They can help identify the root cause and safely prescribe these targeted, non-steroidal therapies for lasting relief.
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I have been suffering from internal itching for 9 years. I have tried medications like Levocetirizine, Cetirizine, Nucort M4, Kenacort injections, and Hydroxyzine, but they only provide temporary relief and the itching returns after 5 days. What alternative medicines should I take for long-lasting relief?

Answered 4 days ago