No, you should not take Oflomac 200 for a headache. Oflomac 200 contains Ofloxacin, which is a strong antibiotic prescribed exclusively to treat bacterial infections. It is not a pain reliever and will have no effect on a headache. Taking antibiotics when they are not needed is ineffective and can lead to unwanted side effects or antibiotic resistance. For a headache, over-the-counter pain relievers such as Paracetamol or Ibuprofen are much safer and more effective. If your headache is severe, persistent, or accompanied by fever, please consult a doctor for proper evaluation.