Both Oframax (Ceftriaxone) and Bigtum (Ceftazidime/Sulbactam) are potent, prescription-only injectable antibiotics that should never be self-administered. A pus-filled leg infection often indicates an abscess, which typically requires physical drainage by a healthcare professional rather than just antibiotics. Choosing between these medications depends on the specific bacteria causing the infection, which can only be determined through a clinical examination or wound culture. Using these strong injections without medical supervision can cause severe side effects and antibiotic resistance. Please visit a doctor immediately for proper evaluation and treatment.