Yes, it is possible that your medications are contributing to this. Hydroxychloroquine (HCQS) is known to sometimes cause itching as a side effect. While prednisolone (Omnacortil) is less likely to cause itching, these symptoms could also be related to your underlying lupus. Please don't worry, but it is important to contact your doctor or rheumatologist. They can help determine the exact cause and safely adjust your treatment. Please do not stop taking your medications without their guidance.
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Could taking HCQS 200 and Omnacortil 2.5 for lupus and amyloidosis be the cause of my newly developed itchy scalp, hands, and legs?