For temporary relief of sharp shoulder pain, you can take over-the-counter anti-inflammatory medications like ibuprofen or naproxen, which help reduce inflammation, or acetaminophen for general pain relief. A topical pain-relieving gel containing diclofenac can also be applied directly to the area. Resting your shoulder and applying an ice pack for 15-20 minutes can provide additional comfort. Since shooting pain can sometimes indicate a pinched nerve, tendonitis, or muscle strain, I highly recommend scheduling an appointment with a doctor for a proper physical exam if the pain persists, worsens, or is accompanied by numbness or tingling.