It is very reasonable to review your treatment, but there is no need to panic. If you wish to replace saxagliptin due to heart and kidney concerns, excellent generic alternatives exist. Within the same drug class, linagliptin is a safer option for kidney health. Alternatively, SGLT2 inhibitors like empagliflozin or dapagliflozin are highly recommended, as they not only lower blood sugar but also actively protect the heart and kidneys. Please consult your prescribing doctor to safely transition to the most appropriate alternative for your health profile, and do not stop taking your current medication abruptly.