For a knee injury, start with the R.I.C.E. method: Rest, Ice, Compression, and Elevation. For pain and swelling, over-the-counter oral anti-inflammatories like generic ibuprofen or naproxen are highly effective. If you prefer to avoid oral medication, you can apply a topical generic diclofenac sodium gel directly to the joint for targeted relief. Generic acetaminophen is also a good alternative for pain management. Always follow package directions. If you experience severe swelling, are unable to bear weight on your leg, or feel the knee giving way, please have a healthcare professional evaluate your knee to rule out any serious ligament damage.