The red and black spots on your hands are common with hand eczema, often representing healing skin, tiny dried blisters, or mild irritation. To treat this, apply a thick, fragrance-free emollient (like petroleum jelly) frequently throughout the day, especially after handwashing. For inflammation and itching, a mild topical corticosteroid cream, such as hydrocortisone, can be applied sparingly. Avoid harsh soaps and wear protective gloves when cleaning. Since hand eczema can sometimes require stronger, prescription-strength treatments, it is best to consult a doctor or dermatologist for a personalized evaluation.