There is no major direct interaction between alcohol and Pankreoflat (Dimethicone + Pancreatin), but since you are already taking medicine for digestive problems, it is better to limit or avoid alcohol. Regular drinking can irritate the stomach, pancreas, and digestive tract, worsening bloating, indigestion, acidity, and abdominal discomfort, and may also delay recovery or increase risks of gastrointestinal and liver issues. If your symptoms continue or get worse, consult your doctor for safe guidance.