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  5. I have been taking paroxetine (25 mg twice daily) and quetiapine (100 mg three times daily) for OCD for two years with a 70% improvement in symptoms. How long should I continue these medications, and how can I safely taper off and discontinue them?

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I have been taking paroxetine (25 mg twice daily) and quetiapine (100 mg three times daily) for OCD for two years with a 70% improvement in symptoms. How long should I continue these medications, and how can I safely taper off and discontinue them?

Asked by Female, 32 · 5 days ago

It is wonderful that you have experienced a 70% improvement. Since you have been stable for two years, discussing a discontinuation plan with your doctor is a reasonable next step. However, because OCD has a high rate of relapse, many clinicians recommend continuing treatment longer, or tapering very gradually. To stop safely, you must never discontinue these medications abruptly. Paroxetine and quetiapine require a slow, step-by-step dose reduction over several weeks or months under your doctor's close supervision to prevent withdrawal symptoms and monitor for any returning OCD symptoms. Please consult your prescribing physician to design a personalized tapering schedule.
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I have been taking paroxetine (25 mg twice daily) and quetiapine (100 mg three times daily) for OCD for two years with a 70% improvement in symptoms. How long should I continue these medications, and how can I safely taper off and discontinue them?

Answered 5 days ago