Mesalamine is generally prescribed as a long-term, maintenance medication to keep Crohn's disease in remission and prevent flare-ups, rather than a short-term cure. Because you are still experiencing abdominal pain and swelling near your navel, your current treatment may need to be adjusted. Persistent symptoms or swelling should be evaluated by your gastroenterologist to check for active inflammation or other localized issues. Please contact your doctor's office to discuss these symptoms so they can safely adjust your treatment plan and help you find relief.