Since strep throat is a bacterial infection, it requires a prescription antibiotic, most commonly penicillin or amoxicillin, to cure the infection and prevent complications. You must see a doctor for a physical exam or rapid swab test to confirm the diagnosis before starting any antibiotics. To manage your throat pain and fever in the meantime, you can take over-the-counter pain relievers like ibuprofen or acetaminophen. Sore throat lozenges, warm liquids, and gargling with salt water will also help soothe the pain. Please do not take leftover antibiotics without a doctor's prescription.