Since Permethrin (including Lupiscab) has not worked after multiple applications, you may be dealing with permethrin resistance, re-infestation, or post-scabetic dermatitis (irritation from overusing the medication). Please consult a dermatologist immediately. You likely need oral Ivermectin, a highly effective prescription pill for resistant scabies, which is sometimes combined with alternative topical treatments like sulfur ointment. It is crucial that all household members are treated simultaneously, and all bedding and clothing are washed in hot water (above 60?C) to prevent re-infection. Stop applying permethrin without medical supervision, as it can cause severe itching that mimics the infection.