Yes, permethrin 5% lotion is safe and correct to apply to the penis and scrotum. It is commonly prescribed to treat conditions like scabies or pubic lice, which cause intense itching. Typically, you should apply it to clean, dry skin from the neck down, covering all areas including the genitals, while avoiding the opening of the urethra. Leave it on for 8 to 14 hours (usually overnight) before washing it off. Some mild, temporary stinging or increased itching can occur. Because you were prescribed two other creams, please call your dermatologist's office to confirm the exact schedule and order of application for your complete treatment.

The active key component present in Pernil 5% Lotion is permethrin 5% w/w, which is an antiparasitic agent.

Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety. For scabies, apply a thin layer to the entire body, excluding the face and scalp unless advised otherwise. Leave it on for 8 to 12 hours, then wash it off. For head lice, if prescribed, apply it to the scalp and hair, leave it on as advised, then rinse thoroughly and comb out lice and eggs. Avoid contact with the eyes and nose, and in case of accidental contact, rinse thoroughly with water.