Yes, experiencing a mild burning, stinging, or dry sensation is a very common and expected reaction when starting this acne gel (which contains clindamycin and benzoyl peroxide). It typically subsides as your skin adapts over the first few weeks, and it is generally safe to continue use. To minimize this irritation, try applying a very thin layer, using a gentle, fragrance-free moisturizer, or applying it every other night initially. However, if the burning is severe, persistent, or accompanied by significant swelling, blistering, or intense redness, please pause the application and consult your dermatologist for guidance.