Yes, this combination is safe and appropriate when taken under medical supervision. Since your cough has lasted 15 days, your doctor is targeting multiple potential causes. The prescription includes a strong cough suppressant and antihistamine (codeine and triprolidine) to relieve the cough, a broad-spectrum antibiotic (cefpodoxime and clavulanic acid) to treat any underlying bacterial infection, and an acid-reducing medication (pantoprazole and domperidone) to protect your stomach and address potential acid reflux, which frequently triggers persistent coughs. Take these exactly as prescribed. Since the cough medicine can cause drowsiness, avoid driving or operating machinery while taking it.