Pramipex 1 Tablet might not seem to work immediately, as it can take several weeks for the medication to reach its full effect. Sometimes the dose may be too low to adequately control your symptoms, or your condition, such as Parkinson’s disease, may be progressing, which can make the medicine feel less effective. It is important to talk to your doctor about your symptoms and response to the medication, and not to change or stop your dose on your own. Your doctor may adjust your dose or consider alternative treatments if needed.

Tingling in the legs with RLS may persist even while on pramipexole if the dose or timing is not optimal. You should consult your doctor to adjust your dose, check your iron levels, and review other treatment options to achieve better symptom control.