These symptoms, sudden blurred vision and new floaters, are not typical side effects of prednisolone and require prompt attention. They could indicate an underlying eye issue, such as retinal changes or inflammation, rather than a direct side effect of your medication. You need an urgent eye evaluation by an ophthalmologist today to ensure your eye is safe. Please do not alter or stop your prednisolone dose without medical supervision, as doing so abruptly can be harmful. Contact your eye doctor or visit an urgent care clinic immediately for a proper exam. This is the safest way to protect your vision.

For neurological conditions, prednisolone dosages are highly personalised based on your specific diagnosis. Typically, a 15-day course starts with a higher dose to quickly control inflammation. This is followed by a gradual step-down (tapering) of the dose over the remaining days to allow your body to adjust safely. It is crucial to follow your doctor's exact schedule and never stop this medication suddenly. Take your dose in the morning with food to prevent sleep issues and stomach upset. Your neurologist will provide your exact daily plan.

For persistent knee swelling, short-term relief can be achieved using nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen, or low-dose oral corticosteroids like prednisone. However, since the swelling has lasted five months, you should consult your rheumatologist. They may recommend a localized corticosteroid injection directly into the knee joint to quickly reduce inflammation. Additionally, they might need to adjust your long-term rheumatoid arthritis treatment, such as disease-modifying antirheumatic drugs (DMARDs) like methotrexate, to better control your condition. Please see your doctor for a tailored evaluation.

Since topical diclofenac gel has not provided relief and you have active swelling without an injury, it is best to consult a doctor to identify the exact cause. For temporary relief, apply a cold compress (ice wrapped in a cloth) to your knee for 15-20 minutes a few times a day, and keep your leg elevated while resting. Over-the-counter oral pain relievers like ibuprofen or paracetamol can help reduce pain and inflammation more effectively than topical gels. Please avoid putting heavy weight on the joint and seek a professional medical evaluation for an accurate diagnosis.

For persistent knee swelling, short-term relief can be achieved using nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen, or low-dose oral corticosteroids like prednisone. However, since the swelling has lasted five months, you should consult your rheumatologist. They may recommend a localized corticosteroid injection directly into the knee joint to quickly reduce inflammation. Additionally, they might need to adjust your long-term rheumatoid arthritis treatment, such as disease-modifying antirheumatic drugs (DMARDs) like methotrexate, to better control your condition. Please see your doctor for a tailored evaluation.

Since topical diclofenac gel has not provided relief and you have active swelling without an injury, it is best to consult a doctor to identify the exact cause. For temporary relief, apply a cold compress (ice wrapped in a cloth) to your knee for 15-20 minutes a few times a day, and keep your leg elevated while resting. Over-the-counter oral pain relievers like ibuprofen or paracetamol can help reduce pain and inflammation more effectively than topical gels. Please avoid putting heavy weight on the joint and seek a professional medical evaluation for an accurate diagnosis.