Daily use of your prescribed medications, a combination of pregabalin with nortriptyline, and your nutritional supplement, is generally safe under medical supervision. Serious liver damage is extremely rare. Since nortriptyline is processed by the liver, mild liver enzyme fluctuations can occasionally occur, but this is seldom a cause for concern. More common, manageable side effects might include drowsiness, dry mouth, or mild dizziness. To ensure your body is processing everything safely, your doctor may suggest routine periodic blood tests. Please continue your treatment as prescribed, and consult your healthcare provider if you experience any unusual fatigue, nausea, or persistent abdominal discomfort.