Since your current regimen of pregabalin and methylcobalamin isn't providing relief, please consult your doctor to discuss these options: 1. Dose Adjustment: Optimising your current pregabalin dosage if you aren't at the maximum limit. 2. Alternative Oral Medications: Swapping to or adding other drug classes, such as duloxetine (an SNRI) or amitriptyline (a tricyclic antidepressant often effective for sleep-disrupting pain). 3. Gabapentin: An alternative gabapentinoid that some patients tolerate better. 4. Topical Options: Lidocaine patches or capsaicin cream for localised relief. Your doctor will help tailor these choices based on your kidney function and overall health.