Spotting on day 16 of your period can commonly be caused by Primolut‑N (norethisterone 5 mg) and is less likely to be caused by Pause (diclofenac 50 mg); diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) and rarely changes spotting but can affect bleeding risk.

⚕️ What this likely is

• Progestogen-related breakthrough bleeding from Primolut‑N is common, especially in the first weeks or with dose changes — this fits spotting during day 16 while taking norethisterone.
• Diclofenac (Pause 50 mg) is unlikely to cause isolated spotting but may slightly alter bleeding tendency.
• Other possibilities (less likely) include pregnancy, infection, or uterine causes if bleeding persists.

💊 What to do now

• Monitor the bleeding for 48–72 hours and note volume, colour, and any pain; record that it began on day 16 while on these drugs.
• Continue or stop medications only per your prescriber's instructions; do not abruptly stop hormonal therapy without consulting your doctor.
• Use sanitary protection; rest and avoid heavy exertion if bleeding increases.
• Contact a gynecologist for tailored advice and to review whether the norethisterone dose/timing is appropriate.

⚠️ Warning signs — seek urgent care

• Heavy bleeding (soaking >1 pad per hour for 2+ hours), fainting/dizziness, or high fever.

🩺 Follow‑up

• When did you start Primolut‑N and Pause, and is the spotting heavier than usual or accompanied by pain?

If you want, I can explain why progestogens cause spotting or how to track bleeding in a simple chart.