You're asking what to do because your period hasn't started one week after finishing estradiol and medroxyprogesterone.

⚕️ What this likely is

• With 7 days of estradiol (estradiol) followed by 14 days of medroxyprogesterone (a progestin), a withdrawal bleed commonly occurs but can be delayed; a short estrogen course sometimes fails to “prime” the lining, producing no or late bleeding.
• Other reasonable possibilities: pregnancy (if sexually active) or underlying anovulation/ hormonal issues (e.g., thyroid, polycystic ovary syndrome).

🏥 What to do now

• Do a urine pregnancy test now if there was any chance of pregnancy.
• Wait an additional 7 days — many withdrawal bleeds appear within 2 weeks of stopping progestin.
• If still no bleeding after 2 weeks, see a gynecologist for evaluation; they may repeat pregnancy testing and consider pelvic exam and basic labs (thyroid, prolactin) or adjust hormones.
• Bring the exact medication names/doses and the dates you took them when you see the doctor.

⚠️ Warning signs — seek urgent care

• Heavy bleeding (soaking >1 pad/hour), severe abdominal pain, fainting, or fever — go to the emergency department.

🩺 Follow-up

• Were you sexually active without reliable contraception during treatment?
• What was the reason for this hormone course (bleeding control vs. HRT vs. contraception)?
• What is your usual cycle length and date of last period before treatment?