Persistent throat irritation despite medicines like montelukast may be due to allergies, postnasal drip, acid reflux, or constant exposure to dust or cold air, so the main trigger may still be present. This can also make you feel tired if the symptoms disrupt your sleep. Try warm fluids, steam, and avoid triggers like dust, smoke, and late-night meals if reflux is suspected. If it is not improving, consult your doctor again so the exact cause can be identified and treatment adjusted.