For chronic pain and mild effusion from an old injury, short-term use of oral nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen can help reduce both pain and joint swelling. Alternatively, applying a topical NSAID gel, such as diclofenac, directly to the ankle is highly effective with fewer side effects. For pain relief without anti-inflammatory action, paracetamol is a safe option. Since this has persisted for 2.5 years, medication should only be a temporary aid. I highly recommend consulting an orthopaedic specialist or physical therapist to evaluate if ankle instability is causing the ongoing oedema and to guide your recovery.

For temporary relief of mild to moderate headache and joint pain, over-the-counter pain relievers can be very helpful. Generic acetaminophen is effective for pain relief and is generally gentle on the stomach. Alternatively, nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or naproxen can help reduce both pain and joint inflammation. Please ensure he has no underlying conditions, like liver issues (for acetaminophen) or stomach ulcers and kidney disease (for NSAIDs), before taking them. It is always safest to consult a doctor or pharmacist to determine the best medication and correct dosage for his specific health history.