After finishing a course of Regestrone (norethisterone), it typically takes about 3 to 10 days for your withdrawal bleed to begin, so two days is still very early. Your lower belly and leg cramps are very common signs that your body is responding to the hormonal shift and preparing to start your period. Since your pregnancy tests are negative, you can feel reassured. Try to rest, stay hydrated, and give your body a few more days. If your period doesn't start within a week, or if the cramps become severe, please consult your healthcare provider.

Norethisterone 5mg dosage depends on the condition being treated. For delaying periods, the standard dose is usually one tablet three times daily, starting three days before your expected period. For heavy menstrual bleeding, it is typically taken two to three times daily for 10 to 14 days. For short-term issues, it is used for just a few days. For conditions like endometriosis, it can be safely taken for 4 to 6 months under strict medical supervision. Long-term use beyond 6 months is generally not recommended without a doctor's re-evaluation to ensure your safety. Please consult your gynecologist for a personalized plan.

After finishing a three-month course of Regestrone (norethisterone), your body is adjusting to shifting hormone levels, which can temporarily cause heavy bleeding and cramping. Additionally, your hypothyroidism can influence your menstrual cycle if thyroid levels aren't fully balanced. The watery discharge might simply be related to these hormonal changes or a mild, easily treatable irritation. Since these symptoms are persistent, I highly recommend gently reaching out to your gynecologist.

Transitioning from Regestrone (norethisterone) to Dronis 30 (ethinyl estradiol/drospirenone) often causes temporary breakthrough bleeding as your body adapts to the new hormone levels. Trapin MF (tranexamic acid/mefenamic acid) helped control the initial flow, but this new spotting is a common adjustment response. Your 4cm ovarian cyst is likely being managed by the Dronis 30, which helps regulate ovarian activity. Please continue taking your Dronis 30 as scheduled. I highly recommend contacting your gynecologist so they can evaluate this bleeding pattern and monitor your cyst with a follow-up ultrasound to ensure everything is resolving safely.

However, once your period has already started and the uterine lining is actively shedding, Regestrone cannot reliably stop the bleeding for just a day or two. Taking it now might only cause irregular spotting or disrupt your natural cycle. For your safety and comfort, it is best to let this cycle finish naturally. Please feel free to consult a doctor to safely plan ahead for any future events!

Since follicles usually rupture when they reach 18 to 24mm, you will likely ovulate within the next 24 to 48 hours. Your previous irregular cycles after taking Regestrone (norethisterone) won't affect this immediate window because the scan shows your body is ready now. To give yourselves the best chance, I recommend having intercourse today, and continuing every other day (or daily) for the next 4 to 5 days (until cycle day 20 or 21). This ensures sperm are waiting when the egg is released.