Irregular or delayed periods can sometimes occur with medicines used for schizophrenia because some of these medicines may affect hormone levels in the body, especially prolactin. Don-LS and Gressami 200 mg may contribute to menstrual irregularities in some women, although stress, weight changes, thyroid problems, PCOS, anaemia, or hormonal imbalance can also affect periods. When hormone levels change, women may experience delayed periods, missed cycles, breast discomfort, or changes in mood and appetite. These effects are not uncommon with certain psychiatric medicines, but treatment should never be stopped suddenly because this may worsen mental health symptoms or cause relapse. A medical review may help determine whether the menstrual changes are medicine-related or due to another hormonal condition. Doctors may sometimes advise hormone tests, prolactin levels, thyroid evaluation, or treatment adjustment depending on overall symptoms and mental health stability. Maintaining proper sleep, nutrition, stress control, and regular follow-up may also support hormonal balance gradually. Consult her doctor if periods remain absent for a long time, pregnancy is suspected, or additional symptoms such as breast discharge or severe weakness develop.