For ear pain and headaches in nose cancer, the choice of painkiller depends on the pain's severity. For mild pain, acetaminophen is usually the safest starting option, as it does not increase bleeding risks. For moderate to severe pain, your oncologist may prescribe stronger options like tramadol or morphine. If the pain is caused by nerve pressure, medications like gabapentin can be very effective. Please consult your treating oncology team before starting any medication, as they will tailor a safe and effective pain management plan specific to your cancer treatment and overall health.