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Amoxycillin+clarithromycin+omeprazole

About Amoxycillin+clarithromycin+omeprazole

Amoxycillin+clarithromycin+omeprazole is used to treat peptic ulcer disease caused by Helicobacter pylori (H. pylori) infection. Peptic ulcers are sores (small, shallow wounds) that form on the inner lining of the stomach and intestine.

Amoxycillin+clarithromycin+omeprazole is a combination of amoxicillin, clarithromycin, and omeprazole. Amoxicillin is a bactericidal antibiotic that eliminates bacteria by blocking the formation of their protective cell wall, which is essential for survival. Clarithromycin, on the other hand, is a bacteriostatic antibiotic that slows bacterial growth rather than killing them. It does this by inhibiting protein synthesis, preventing bacteria from multiplying and spreading. Omeprazole is a proton pump inhibitor that reduces stomach acid by blocking the gastric proton pump enzyme, which is responsible for acid production.

Take Amoxycillin+clarithromycin+omeprazole for the duration prescribed by your doctor, based on your medical condition. Some common side effects may include nausea, diarrhoea, vomiting, stomach pain, altered taste, dizziness, and headache. These side effects are often minimal and commonly resolve on their own. However, if they continue or become severe, seek medical advice.

Inform your doctor before using Amoxycillin+clarithromycin+omeprazole if you have a history of liver, kidney disease, myasthenia gravis (a neuromuscular disorder), or mononucleosis. Avoid taking this medication during pregnancy or breastfeeding unless prescribed by your doctor. As it may cause drowsiness, drive only if you feel fully alert. This medication is not recommended for children due to a lack of safety data. Avoid alcohol consumption while taking it, as it can increase drowsiness and stimulate stomach acid production. Keep your doctor updated on your medications and health condition to prevent potential side effects.

Uses of Amoxycillin+clarithromycin+omeprazole

Amoxycillin+clarithromycin+omeprazole is used to treat and prevent the return of peptic ulcer disease.

Medicinal Benefits

Amoxycillin+clarithromycin+omeprazole is a combination of three medications: amoxicillin, clarithromycin, and omeprazole. Amoxicillin is a bactericidal antibiotic that kills bacteria by preventing the formation of their protective cell wall, essential for survival. Clarithromycin is a bacteriostatic antibiotic that slows bacterial growth by inhibiting protein synthesis, preventing bacteria from multiplying. Omeprazole, a proton pump inhibitor, reduces stomach acid by blocking the gastric proton pump enzyme responsible for acid production. Together, these medications effectively treat peptic ulcer disease caused by H. pylori infection.

Directions for Use

• Amoxycillin+clarithromycin+omeprazole should usually be taken before a meals. • Amoxycillin+clarithromycin+omeprazole is usually taken twice a day, or as prescribed by your doctor. • Swallow Amoxycillin+clarithromycin+omeprazole as a whole with a glass of water. • Do not break, chew or crush Amoxycillin+clarithromycin+omeprazole.

Side Effects of Amoxycillin+clarithromycin+omeprazole

  • Nausea
  • Vomiting
  • Stomach pain
  • Headache
  • Diarrhoea
  • Change in ability to taste food

Drug Warnings

Do not use Amoxycillin+clarithromycin+omeprazole if you are allergic to any of its ingredients. Inform your doctor before taking Amoxycillin+clarithromycin+omeprazole if you have a history of liver or kidney disease, myasthenia gravis (a neuromuscular disorder),  or mononucleosis. If you are pregnant or breastfeeding, inform your doctor before use. Amoxycillin+clarithromycin+omeprazole may cause drowsiness, so drive only if you feel fully alert. This medication is not recommended for children due to a lack of safety data. Avoid alcohol consumption while taking Amoxycillin+clarithromycin+omeprazole, as it may increase drowsiness and stimulate stomach acid production.

Drug Interactions

Drug-Drug Interaction: Amoxycillin+clarithromycin+omeprazole may interact with antigout (colchicine), antipsychotic (pimozide), anticoagulants (warfarin), antiarrhythmics (digoxin), antiretroviral (atazanavir, nelfinavir) and lipid-lowering agents (simvastatin, lovastatin).

Drug-Food Interaction: Avoid intake of cranberry, smoking and alcohol, as alcohol can increase stomach acid production, worsening acidity, and heartburn.

Drug-Disease Interaction: Before using Amoxycillin+clarithromycin+omeprazole, inform your doctor if you have a history of heart, liver or kidney disease, myasthenia gravis (a neuromuscular disorder) or mononucleosis, immunity disorder (SLE) and other pre-existing medical conditions.

Drug-Drug Interactions Checker List:

  • PIMOZIDE
  • COLCHICINE
  • DIGOXIN
  • ATAZANAVIR
  • NELFINAVIR
  • LOVASTATIN
  • SIMVASTATIN
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Avoid consumption of alcohol with Amoxycillin+clarithromycin+omeprazole as it may increase drowsiness. Please consult a doctor before consuming alcohol with Amoxycillin+clarithromycin+omeprazole.

    • Safety Warning

      Pregnancy

      caution

      Please consult a doctor if you are pregnant or planning to become pregnant. Your doctor will prescribe only if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      There is limited information on how Amoxycillin+clarithromycin+omeprazole affects breastfeeding. Please consult your doctor before taking Amoxycillin+clarithromycin+omeprazole if you are a breastfeeding mother.

    • Safety Warning

      Driving

      caution

      Amoxycillin+clarithromycin+omeprazole may cause dizziness. Therefore, avoid driving if you feel dizzy after taking Amoxycillin+clarithromycin+omeprazole.

    • Safety Warning

      Liver

      caution

      Consult your doctor before taking Amoxycillin+clarithromycin+omeprazole if you have a liver impairment or any concerns regarding this.

    • Safety Warning

      Kidney

      caution

      Consult your doctor before taking Amoxycillin+clarithromycin+omeprazole if you have a kidney problem or any concerns regarding this.

    • Safety Warning

      Children

      caution

      Amoxycillin+clarithromycin+omeprazole should not be given to children as safety and effectiveness were not established. Please consult your doctor before giving Amoxycillin+clarithromycin+omeprazole to your child.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Eat smaller, more frequent meals.
    • Avoid smoking and alcohol consumption as alcohol can increase stomach acid production, leading to acidity and heartburn.
    • Drink plenty of water.
    • Limit foods with high cholesterol and saturated fats.
    • Limit foods that trigger acidity, such as high-fat, spicy foods, chocolates, citrus fruits, pineapple, tomatoes, onions, garlic, tea, and soda.
    • Avoid prolonged sitting, as it can worsen acidity. Take a short break every hour to stretch or walk briskly.

    Special Advise

    Patients Concern

    Disease/Condition Glossary

    Peptic Ulcers: Peptic ulcers are open sores that form on the lining of the stomach or small intestine due to the erosion of the protective stomach lining. Common symptoms include nausea, appetite changes, dark or bloody stools, unexplained weight loss, vomiting, and persistent indigestion-like pain. This pain can be brief or last for hours, often worsening on an empty stomach or right after eating. If left untreated, peptic ulcers can lead to serious complications such as internal bleeding, peritonitis (a hole in the stomach or intestinal wall), and pyloric stenosis (narrowing of the stomach or duodenum due to chronic inflammation).

    FAQs

    Amoxycillin+clarithromycin+omeprazole is prescribed to treat peptic ulcer disease caused by an infection with Helicobacter pylori (H. pylori), a common type of bacteria.

    Amoxycillin+clarithromycin+omeprazole contains amoxicillin, clarithromycin, and omeprazole. Amoxicillin kills bacteria by blocking cell wall formation, while clarithromycin slows their growth by inhibiting protein synthesis. Omeprazole, a type of proton pump inhibitor, lowers stomach acid production. Together, they treat peptic ulcers caused by H. pylori infection.

    You are recommended to avoid alcohol consumption while taking Amoxycillin+clarithromycin+omeprazole as it may worsen side effects, reduce antibiotic effectiveness, and irritate the stomach. If you have any questions or concerns about this, consult your doctor.

    If your condition does not improve after completing the entire course of Amoxycillin+clarithromycin+omeprazole inform your doctor. Also, notify them if your symptoms worsen during treatment. Your doctor may examine your condition, recommend further tests, or adjust your treatment if needed.

    The common side-effects of Amoxycillin+clarithromycin+omeprazole are headache, nausea, diarrhoea, stomach discomfort, and dizziness. These side effects are usually mild and temporary. However, if any of these side effects persist or worsen, please contact your doctor immediately.

    Taking higher doses than prescribed is ineffective and may cause side effects. Therefore, it's essential to follow the dosage instructions provided by your doctor to ensure safe and effective use.

    Available Medicines for

    Amoxycillin+clarithromycin+omeprazole

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