About ATORVASTATIN+FOLIC ACID+METHYLCOBALAMIN+PYRIDOXINE HYDROCHLORIDE
ATORVASTATIN+FOLIC ACID+METHYLCOBALAMIN+PYRIDOXINE HYDROCHLORIDE is a combination of medications used to treat Hyperlipidemia (an excess of lipids in the blood) and Hyperhomocysteinemia (high levels of homocysteine, an amino acid linked to cardiovascular diseases due to deficiencies of vitamins). Hyperlipidaemia, often known as high cholesterol, occurs when your blood has an abnormally high level of a fatty component called cholesterol. Too much cholesterol might cause blood vessel blockage. It increases your chances of having heart problems or having a stroke.
ATORVASTATIN+FOLIC ACID+METHYLCOBALAMIN+PYRIDOXINE HYDROCHLORIDE contains Atorvastatin, Folic Acid, Methylcobalamin and Pyridoxine hydrochloride. Atorvastatin is a lipid-lowering medicine that works by blocking an enzyme (HMG-CoA-reductase) required to make cholesterol. Thus ATORVASTATIN+FOLIC ACID+METHYLCOBALAMIN+PYRIDOXINE HYDROCHLORIDE lowers the amount of fat or cholesterol deposition (plaque) in the heart's arteries, thereby reducing the chance of having a heart attack or stroke in the future. Folic Acid, Methylcobalamin and Pyridoxine hydrochloride collectively reduce Homocysteine levels. Thus, it aids in the treatment of hyperhomocysteinemia.
Take ATORVASTATIN+FOLIC ACID+METHYLCOBALAMIN+PYRIDOXINE HYDROCHLORIDE as prescribed by your doctor. Depending on your medical condition, you are advised to take ATORVASTATIN+FOLIC ACID+METHYLCOBALAMIN+PYRIDOXINE HYDROCHLORIDE for as long as your doctor prescribes it. In some cases, ATORVASTATIN+FOLIC ACID+METHYLCOBALAMIN+PYRIDOXINE HYDROCHLORIDE may cause side effects such as feeling sick (nausea), indigestion, headaches, nosebleeds, sore throat, cold-like symptoms, constipation or farting (flatulence) and diarrhoea. Most of these side effects of ATORVASTATIN+FOLIC ACID+METHYLCOBALAMIN+PYRIDOXINE HYDROCHLORIDE do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.
Before taking the ATORVASTATIN+FOLIC ACID+METHYLCOBALAMIN+PYRIDOXINE HYDROCHLORIDE, inform your doctor about all your allergic or hypersensitivity reactions to medicines or food. ATORVASTATIN+FOLIC ACID+METHYLCOBALAMIN+PYRIDOXINE HYDROCHLORIDE should not be used in pregnant and nursing mothers unless necessary. So, inform your doctor if you are pregnant or nursing mother. Your doctor will weigh the benefits and potential risks before prescribing ATORVASTATIN+FOLIC ACID+METHYLCOBALAMIN+PYRIDOXINE HYDROCHLORIDE. Before taking ATORVASTATIN+FOLIC ACID+METHYLCOBALAMIN+PYRIDOXINE HYDROCHLORIDE, inform your doctor about your medical history, especially if you are suffering from liver disease, rhabdomyolysis (muscle injury), and other medications you are currently taking to rule out any potential negative effects. Do not stop using ATORVASTATIN+FOLIC ACID+METHYLCOBALAMIN+PYRIDOXINE HYDROCHLORIDE without consulting the doctor; it will not cause withdrawal symptoms. However, stopping atorvastatin may cause your cholesterol to rise. This increases your risk of heart attacks and strokes.
Uses of ATORVASTATIN+FOLIC ACID+METHYLCOBALAMIN+PYRIDOXINE HYDROCHLORIDE
Hyperlipidemia (High cholesterol) and Hyperhomocysteinemia (high levels of homocysteine).
Medicinal Benefits
ATORVASTATIN+FOLIC ACID+METHYLCOBALAMIN+PYRIDOXINE HYDROCHLORIDE contains Atorvastatin, Folic Acid, Methylcobalamin, and Pyridoxine hydrochloride. Atorvastatin is a lipid-lowering medication that inhibits an enzyme (HMG-CoA-reductase) essential for cholesterol production. Thus, ATORVASTATIN+FOLIC ACID+METHYLCOBALAMIN+PYRIDOXINE HYDROCHLORIDE reduces the amount of fat or cholesterol deposition (plaque) in the heart's arteries, lowering the risk of having a heart attack or stroke in the future. Folic Acid, Methylcobalamin and Pyridoxine hydrochloride work together to lower homocysteine levels. Thus, it aids in the treatment of hyperhomocysteinemia. In hyperlipidemic patients, it is used with lifestyle changes to reduce lipid levels.
Directions for Use
Storage
Side Effects of ATORVASTATIN+FOLIC ACID+METHYLCOBALAMIN+PYRIDOXINE HYDROCHLORIDE
- Feeling sick (nausea)
- Indigestion
- Headaches
- Nosebleeds
- Sore throat
- Cold-like symptoms (runny nose, blocked nose or sneezing)
- Constipation
- Farting (flatulence)
- Diarrhoea
In-Depth Precautions and Warning
Drug Warnings
Before taking the ATORVASTATIN+FOLIC ACID+METHYLCOBALAMIN+PYRIDOXINE HYDROCHLORIDE, inform your doctor about all your allergic or hypersensitivity reactions to medicines or food. And also, tell your doctor about your medical history and other medications you are taking to rule out any potential negative effects. Inform your doctor if you suffer from liver disease, rhabdomyolysis (muscle injury) and anaemia (lack of blood).
Drug Interactions
Drug-Drug Interactions: ATORVASTATIN+FOLIC ACID+METHYLCOBALAMIN+PYRIDOXINE HYDROCHLORIDE may have interaction with HIV medications (e.g. atazanavir, darunavir), antibiotics (e.g. clarithromycin), immunosuppressive agents (e.g. cyclosporine) and anticancer medication (e.g. capecitabine, fluorouracil),
Food-Drug Interactions: ATORVASTATIN+FOLIC ACID+METHYLCOBALAMIN+PYRIDOXINE HYDROCHLORIDE may interact with grapefruit. It increases the concentration of ATORVASTATIN+FOLIC ACID+METHYLCOBALAMIN+PYRIDOXINE HYDROCHLORIDE in your body.
Drug-Disease Interactions: ATORVASTATIN+FOLIC ACID+METHYLCOBALAMIN+PYRIDOXINE HYDROCHLORIDE may interact with conditions like liver disease, rhabdomyolysis (muscle injury) and anaemia (lack of blood).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionDo not drink too much alcohol while taking this medicine.
Pregnancy
cautionATORVASTATIN+FOLIC ACID+METHYLCOBALAMIN+PYRIDOXINE HYDROCHLORIDE should not be used when pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing ATORVASTATIN+FOLIC ACID+METHYLCOBALAMIN+PYRIDOXINE HYDROCHLORIDE.
Breast Feeding
cautionLet your doctor know if you are a nursing mother before taking ATORVASTATIN+FOLIC ACID+METHYLCOBALAMIN+PYRIDOXINE HYDROCHLORIDE; your doctor will decide whether breastfeeding mothers can take ATORVASTATIN+FOLIC ACID+METHYLCOBALAMIN+PYRIDOXINE HYDROCHLORIDE or not.
Driving
not applicableATORVASTATIN+FOLIC ACID+METHYLCOBALAMIN+PYRIDOXINE HYDROCHLORIDE has negligible influence on the ability to drive and use machines.
Liver
cautionInform your doctor before receiving the ATORVASTATIN+FOLIC ACID+METHYLCOBALAMIN+PYRIDOXINE HYDROCHLORIDE if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending on your current liver conditions.
Kidney
cautionInform your doctor before receiving the ATORVASTATIN+FOLIC ACID+METHYLCOBALAMIN+PYRIDOXINE HYDROCHLORIDE if you have had a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.
Children
cautionATORVASTATIN+FOLIC ACID+METHYLCOBALAMIN+PYRIDOXINE HYDROCHLORIDE is not indicated in the treatment of patients below the age of 10 years.
Habit Forming
Diet & Lifestyle Advise
- Try aromatherapy, yoga, and meditation to help relax your body and mind.
- Try to do breathing exercises to get more oxygen.
- Eat a healthy diet rich in soluble fibre like beans, legumes, whole grains, flax, apples, and citrus fruits.
- Try to replace most of your saturated fats with unsaturated fats that can reduce total cholesterol and LDL cholesterol quickly; avocados, olive oil, fatty fish, and nuts contain lots of heart-healthy unsaturated fats, so it’s beneficial to eat them regularly.
- Try to adopt a Mediterranean-style diet rich in olive oil, fruits, vegetables, nuts, whole grains, and fish, and low in red meat and most dairy.
- Try to give priority to more fruits and veggies in your daily meal as these contain antioxidants which help to lower LDL
- Minimize the intake of added sugar. The American Heart Association (ADA) recommends one should not eat more than 100 calories (25 grams) of added sugar for women and children and no more than 150 calories (37.5 grams) for men every day.
- American Heart Association recommends that sodium chloride (table salt) intake not exceed 2,300 mg per day as part of a healthy eating pattern.
- As a precautionary measure, do not consume alcohol and quit smoking.
Patients Concern
Disease/Condition Glossary
High cholesterol: Cholesterol is a waxy substance produced by the liver to protect nerves, make tissue, and various hormones. Our body also receives cholesterol from food, like cooking oils, eggs, meats, and dairy products. Excess cholesterol is bad for our health. There are two types of cholesterol: ' bad cholesterol' and 'good cholesterol'. Bad cholesterol comprises low-density lipoprotein (LDL) and triglycerides (TG), while good cholesterol consists of high-density lipoprotein (HDL). Usually, there are no specific symptoms of raised or high cholesterol levels but a large deposition of cholesterol in the arteries (plaque) or heart blockage. Blocked artery or plaque formation in the heart's arteries can lead to chest pain (angina), heart attack, or stroke. So it is advisable to have complete cholesterol tests (lipid profile tests) at least once a year. It will help you closely monitor your heart health and risk of heart attack and stroke.
Hyperhomocysteinemia: Hyperhomocysteinemia refers to the condition where there is greater than 15 micromol/L of homocysteine in the blood. This condition is present in a wide range of diseases, and in many cases, it is an independent risk factor for more serious medical conditions. Hyperhomocysteinemia itself does not have any symptoms, but if it develops due to a deficiency in vitamins B6, B12, or folate, a person may experience: weakness, dizziness, and sores on the mouth or tongue.
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