Dextromethorphan+triprolidine
About Dextromethorphan+triprolidine
Dextromethorphan+triprolidine is a combination of medications primarily used to treat dry cough. It is also used to treat runny or stuffy nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu. Coughing (dry or productive) is the body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. There are two types of coughs: Dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) means mucous or sputum is created to help clear your airways.
Dextromethorphan+triprolidine is a combination of two drugs: Dextromethorphan (cough suppressant) and Triprolidine (antihistamine). Dextromethorphan belongs to the class of cough suppressants that works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough, and Triprolidine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.
Take Dextromethorphan+triprolidine as prescribed by your doctor. Your doctor will recommend how often you take Dextromethorphan+triprolidine based on your medical condition. Some people may experience nausea, vomiting, drowsiness, stomach upset, dizziness, difficulty sleeping, nervousness, or excitation. Most of these side effects of Dextromethorphan+triprolidine do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Inform your doctor if you are allergic to Dextromethorphan+triprolidine or any other medicines, if you are breastfeeding, pregnant or planning pregnancy. Dextromethorphan+triprolidine should be used with caution in children. Avoid using Dextromethorphan+triprolidine if you have taken medicines for Parkinson’s disease or depression, such as phenelzine, selegiline, rasagiline, isocarboxazid, and tranylcypromine for the past 14 days. You are advised to avoid or limit caffeine intake with Dextromethorphan+triprolidine as it may increase the adverse effects. If you have asthma, emphysema (a lung condition causing shortness of breath), cough with excessive mucus, or cough caused by smoking, inform your doctor before taking Dextromethorphan+triprolidine.
Uses of Dextromethorphan+triprolidine
• Cough Suppression: Dextromethorphan+triprolidine helps to reduce persistent coughing by acting on the brain's cough center.
• Allergy Relief: Dextromethorphan+triprolidine provides allergy relief from symptoms like a runny nose, sneezing, and itchy eyes.
• Cold & Flu Symptom Management: Dextromethorphan+triprolidine is used to ease discomfort caused by seasonal allergies, colds, and flu.
Medicinal Benefits
Dextromethorphan+triprolidine is a combination of two drugs, namely Dextromethorphan and Triprolidine. Dextromethorphan belongs to the class of cough suppressants that works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough, which decreases the urge to cough. Triprolidine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions and provides relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stuffiness.
Directions for Use
Storage
Side Effects of Dextromethorphan+triprolidine
• Drowsiness
• Dizziness
• Stomach upset
• Difficulty in sleeping
• Nervousness and excitable
Drug Warnings
Inform your doctor if you are allergic to Dextromethorphan+triprolidine or any other medicines, if you are breastfeeding, pregnant or planning pregnancy. Dextromethorphan+triprolidine should be used with caution in children. Avoid using Dextromethorphan+triprolidine if you have taken medicines for Parkinson’s disease or depression, such as phenelzine, selegiline, rasagiline, isocarboxazid, and tranylcypromine for the past 14 days. You are advised to avoid or limit caffeine intake with Dextromethorphan+triprolidine as it may increase the adverse effects. If you have asthma, emphysema (a lung condition causing shortness of breath), cough with excessive mucus, or cough caused by smoking inform your doctor before taking Dextromethorphan+triprolidine. Caution is advised when drinking grapefruit juice or eating grapefruit as it can lead to excessive accumulation of the drug with both increased and prolonged effects.
Drug Interactions
Drug-Drug Interaction: Dextromethorphan+triprolidine may have interaction with anti-allergic drugs (diphenhydramine, chlorpheniramine, promethazine), narcotic analgesics (hydrocodone, codeine, morphine), central nervous system stimulants (methylphenidate), antidepressants (duloxetine, sertraline, escitalopram), bronchodilators (tiotropium), medicines used to treat irregular heartbeats (quinidine), anticonvulsants (pregabalin), antianxiety drug (alprazolam), antipsychotics (quetiapine).
Drug-Food Interaction: Avoid or limit the intake of chocolate and caffeine-containing foods such as cocoa beans and tea leaves with Dextromethorphan+triprolidine as they may increase the risk of severity of side effects. Also, avoid consumption of alcohol with Dextromethorphan+triprolidine as it may increase the risk of adverse effects such as drowsiness, dizziness, or difficulty in concentrating. Avoid drinking grapefruit juice or eating grapefruit as it can lead to excessive accumulation of the drug with both increased and prolonged effects.
Drug-Disease Interaction: If you have asthma, emphysema (a lung condition causing shortness of breath), cough with excessive mucus, or cough caused by smoking, inform your doctor before taking Dextromethorphan+triprolidine.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consumption of alcohol with Dextromethorphan+triprolidine as it may increase drowsiness. Please consult a doctor before consuming alcohol with Dextromethorphan+triprolidine.
Pregnancy
consult your doctorThe safety of Dextromethorphan+triprolidine in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.
Breast Feeding
safe if prescribedIt is unknown whether Dextromethorphan+triprolidine is excreted in human milk. Dextromethorphan+triprolidine is given to breastfeeding mothers only if the doctor thinks the benefits outweigh the risks.
Driving
cautionDextromethorphan+triprolidine may cause dizziness or drowsiness in some people. Therefore, drive only if you are alerted after taking the Dextromethorphan+triprolidine.
Liver
consult your doctorTake Dextromethorphan+triprolidine with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust the dose as required.
Kidney
safe if prescribedIf you have any concerns regarding the use of Dextromethorphan+triprolidine in patients with Kidney problems, please consult a doctor.
Children
cautionDo not use Dextromethorphan+triprolidine in children younger than 6 years without consulting your doctor.
Habit Forming
Diet & Lifestyle Advise
- Avoid dairy products such as milk, as it may increase mucus production. Also, avoid processed or refined foods to relieve cough. Instead, replace baked foods, fried foods, white bread, white pasta, French fries, sugary desserts and chips with green leafy vegetables.
- Drink plenty of fluids to avoid dry throat while you cough and loosen mucus.
- Avoid citrus fruits as they may worsen the cough. Eat fruits rich in water content, such as pears, watermelon, peaches and pineapples.
Special Advise
You are recommended to consult a doctor if the cough persists or worsens after 1 week of treatment with Dextromethorphan+triprolidine.
Patients Concern
Disease/Condition Glossary
Cough: Also known as tussis, is a voluntary or involuntary act and the body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. Coughs may be dry or productive. A productive cough (wet cough) brings up sputum (phlegm, mucus, and other matter) from the lungs. Cough is commonly caused as a response to allergy or viral infection but coughing up mucus is possibly an indication of infection in the respiratory tract. If you cough thick, solid white mucus, you may have a bacterial infection in the airways. If the mucus is clear or light-coloured, you may have allergies or a minor infection in the respiratory tract, and yellow or green mucus indicates a respiratory infection.
Allergies: These occur when foreign elements known as allergens attack and invade our body, thereby causing the release of histamines. This chemical messenger 'histamines' causes swelling, inflammation, redness, itchiness, itchy/watery nose, and throat, and watery eyes. Allergies generally occur due to chemicals, air pollution, pet dander, dust, pollen hairs, seasonal allergies like hay fever, etc.
FAQs
Dextromethorphan+triprolidine is used to treat dry cough and allergic symptoms such as sneezing, runny nose, throat irritation, or watery eyes.
Dextromethorphan+triprolidine contains Dextromethorphan and Triprolidine. Dextromethorphan belongs to the class of cough suppressants that works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough. Thus, decreases the urge to cough. Triprolidine is an antihistamine (anti-allergic drug) that blocks the action of histamine, a substance responsible for causing allergic reactions and provides relief from symptoms of allergy.
Dextromethorphan+triprolidine may be used to relieve allergic symptoms such as sneezing, runny or stuffy nose, throat irritation, or watery eyes. It contains Triprolidine, an anti-allergic drug that blocks the action of histamine, a substance responsible for causing allergic reactions.
Yes, Dextromethorphan+triprolidine may cause dizziness in some people. It is not necessary for everyone taking Dextromethorphan+triprolidine to experience this side effect. However, avoid driving or operating heavy machinery if you feel dizzy after taking Dextromethorphan+triprolidine.
You are recommended to take Dextromethorphan+triprolidine for as long as your doctor has prescribed it. However, if the symptoms persist or worsen with rash, fever or persistent headache after using Dextromethorphan+triprolidine, please consult your doctor.
You are not recommended to take Dextromethorphan+triprolidine with duloxetine (antidepressant) as it may lead to a severe condition called serotonin syndrome and symptoms like blurred vision, stomach cramps, diarrhoea, hallucination, extreme changes in blood pressure, confusion, excessive sweating, increased heart rate, fever, shivering or shaking, tremor, incoordination, muscle spasm or stiffness. However, please consult a doctor before taking Dextromethorphan+triprolidine with other medicines.
No, you are not recommended to stop taking Dextromethorphan+triprolidine without consulting your doctor, as it may worsen your cough or cause recurring symptoms. Therefore, take Dextromethorphan+triprolidine for as long as your doctor has prescribed it, and if you experience any difficulty while taking Dextromethorphan+triprolidine, please consult your doctor.
Store Dextromethorphan+triprolidine at room temperature away from moisture and heat. Keep out of reach of children.
The common side effects of Dextromethorphan+triprolidine are nausea, vomiting, drowsiness, stomach upset, dizziness, difficulty in sleeping, nervousness, or excitation. If any of these side effects persist or worsen, please consult your doctor.
