DI IODOHYDROXYQUINOLINE belongs to a group of medications called 'antiprotozoal agents' used to treat Amoebiasis, also known as amebic dysentery. Amebiasis, or amebic dysentery, is an intestinal disease caused by protozoa called 'Entamoeba histolytica'.
DI IODOHYDROXYQUINOLINE contains 'Di Iodohydroxyquinonlione' that acts against intestinal (lumen) amoeba that forms cysts. DI IODOHYDROXYQUINOLINE is poorly absorbed by your intestine and remains in the intestine at a very high concentration. It interferes with the enzymes required for the amoeba's survival in the intestine and forms iron chelate (complex compound), killing amoeba cells and destroying their outer cell wall (cyst) layer. Besides this, it also enhances zinc absorption in the intestine and forms complex chelate of zinc ions which also help destroy amoeba cells.
DI IODOHYDROXYQUINOLINE should be taken preferably after meals to avoid gastric irritation. Vomiting, abdominal cramps, diarrhoea, skin itchiness, fever, chills, headache, dizziness and an enlarged thyroid are some of the common side effects of DI IODOHYDROXYQUINOLINE, which can occur in some patients. These side effects are mild and temporary and go off after some time. However, if these side effects persist, contact your doctor.
Do not take DI IODOHYDROXYQUINOLINE if you are allergic to 'iodine', 'Di Iodohydroxyquinonlione', or any other components present in DI IODOHYDROXYQUINOLINE. Before taking this medicine, inform your doctor if you have thyroid problems, as this medicine contains Iodine and may interfere with some thyroid tests. Taking a higher dose of DI IODOHYDROXYQUINOLINE by people with optic neuropathy can cause serious optic neuritis. Inform your doctor if you have liver or kidney problems. Tell your doctor if you are pregnant or breastfeeding. Inform your doctor if you take any prescription or non-prescription medicines, herbal products or dietary supplements.
Intestinal Amoebiasis (Amebic Dysentery)
DI IODOHYDROXYQUINOLINE contains 'Di Iodohydroxyquiononlione', which is antiprotozoal and amebicidal in nature. It acts against growing amoeba, which survives in our intestines and causes diarrhoea. DI IODOHYDROXYQUINOLINE forms a chelate or complex compound of iron and zinc in the intestine, which interferes with amoeba working, and thus these protozoa get killed. It is also used to treat Balantidiasis, bacterial and fungal infections.
Do not take DI IODOHYDROXYQUINOLINE if you are allergic to 'Di Iodohydroxyquinoline', 'iodine' or any ingredients present in it. Also, it should not be used in patients with liver failure, kidney failure, and chronic diarrhoea, especially in children. It should be cautioned in patients with thyroid problems and neurological disorders (diseases associated with the brain and spinal cord). It is also not recommended for long-term use.
Drug-drug interactions: No interactions found or established.
Drug-food interactions: Alcohol consumption may increase the risk of side effects.
Drug-disease interactions: DI IODOHYDROXYQUINOLINE should be used with caution in patients with thyroid problems, liver failure, and optic neuropathy (an eye disease).
Alcohol consumption may increase the risk of side effects and worsen your condition.
Please consult your doctor. There are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe DI IODOHYDROXYQUINOLINE only if the benefits outweigh the risks.
Consult your doctor, and there is no substantial research yet on the use of DI IODOHYDROXYQUINOLINE in breastfeeding/nursing mothers.
DI IODOHYDROXYQUINOLINE may not affect your ability to drive.
There is limited research on the usage of DI IODOHYDROXYQUINOLINE in patients with liver disease. Please consult your physician.
There is limited research on the usage of DI IODOHYDROXYQUINOLINE in patients with kidney disease. Please consult your physician.
DI IODOHYDROXYQUINOLINE should be used with caution in children below 12 years of age. Your doctor will decide the dose of DI IODOHYDROXYQUINOLINE based on your child's condition.
Amoebic dysentery: It is an intestinal (bowel) illness caused by a parasite (amoeba) known as Entamoeba histolytica spread through human faeces (poop). Usually, there are no symptoms, but sometimes it causes diarrhoea (loose stool/poop), nausea (a feeling of sickness in the stomach) and weight loss.
Balantidiasis: Balantidiasis is the inflammation of the large intestine (colon) caused by Balantidium coli. Symptoms include chronic diarrhoea, nausea, abdominal pain and weight loss.