Dapagliflozin+vildagliptin+metformin
About Dapagliflozin+vildagliptin+metformin
Dapagliflozin+vildagliptin+metformin is an antidiabetic medicine used to treat diabetes. It is used for the treatment of Type II Diabetes. Type II Diabetes Mellitus is a chronic condition that influences the body's metabolism of glucose or blood sugar. Insulin resistance or insufficient insulin production are the two main causes of type 2 diabetes.
Dapagliflozin+vildagliptin+metformin contains Dapagliflozin (sodium-glucose cotransporter-2 inhibitors), Vildagliptin (dipeptidyl peptidase-4 inhibitor), and Metformin (biguanides), which work by increasing the amounts of certain natural substances that lower blood sugar when it is high.
Dapagliflozin+vildagliptin+metformin may cause certain side effects, such as vomiting, nausea, abdominal pain, headache, frequent urination, and allergic reactions. If these side effects persist or worsen, please consult your doctor. Dapagliflozin+vildagliptin+metformin should be taken as prescribed by your doctor.
Dapagliflozin+vildagliptin+metformin should be avoided if you are allergic to any of the medicines or their components. Inform your doctor about your medical history and the medicines you are taking, including herbs and supplements, before starting the treatment with Dapagliflozin+vildagliptin+metformin. This can help prevent unwanted effects. Let your doctor know if you are pregnant or breastfeeding before taking Dapagliflozin+vildagliptin+metformin. It is not recommended for use in children below 18 years of age.
Uses of Dapagliflozin+vildagliptin+metformin
Medicinal Benefits
Dapagliflozin+vildagliptin+metformin is a combination of three drugs, namely: Dapagliflozin, Vildagliptin, and Metformin. Dapagliflozin+vildagliptin+metformin belongs to the group of anti-diabetic medicines used to treat type-2 diabetes mellitus. Vildagliptin enhances glucose-mediated insulin secretion, thereby reducing fasting and post-prandial blood sugar concentrations. Dapagliflozin helps remove excess sugar from the body via urine. Metformin helps reduce the sugar production by cells in the liver and delays sugar absorption from the intestines.
Directions for Use
Storage
Side Effects of Dapagliflozin+vildagliptin+metformin
- Headache
- Nausea
- Stomach upset
- Vomiting
- Abdominal pain
- Allergic reactions
- Painful urination
- Hypoglycaemia (low blood sugar)
Drug Warnings
Dapagliflozin+vildagliptin+metformin should be avoided if you are allergic to any of the medicines or their components. Before starting the treatment, inform your doctor about your medical history and the medications you take, including herbs and supplements, to rule out any side effects. It is unknown whether Dapagliflozin+vildagliptin+metformin can be given to pregnant women or breastfeeding mothers. Hence, inform your doctor if you are pregnant or breastfeeding. It is not recommended for use in children below 18 years of age. Avoid drinking alcohol while on Dapagliflozin+vildagliptin+metformin as it increases the risk of hypoglycemia and lactic acidosis (when the lactic acid increases in the body, which impacts the functioning of various organs in the body). Inform your doctor if you have any liver/kidney disease, heart problems, and hypertension before taking Dapagliflozin+vildagliptin+metformin.
Drug Interactions
Drug-Drug Interactions: Dapagliflozin+vildagliptin+metformin interacts with an anti-depressant (bupropion), drugs used to treat glaucoma, antibiotics (cephalexin, ciprofloxacin), anti-acidity drugs (cimetidine), heart condition drugs (digoxin), anti-epileptic drugs (topiramate, lamotrigine), heart-related chest medicine (ranolazine).
Drug-Food Interactions: Intake of excessive alcoholic beverages may increase the chance of a life-threatening condition known as Lactic acidosis. So, avoid intake of alcoholic beverages with Dapagliflozin+vildagliptin+metformin.
Drug-Disease Interactions: Inform your doctor if you have any kidney or liver disease or heart problems.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAlcohol increases the impact of metformin on lactate metabolism. Hence, you should not consume excessive amounts of alcohol, either temporarily or permanently, while taking Dapagliflozin+vildagliptin+metformin.
Pregnancy
consult your doctorThere are no adequate studies on the effect of Dapagliflozin+vildagliptin+metformin in pregnancy. If you are pregnant or planning pregnancy, inform your doctor before taking Dapagliflozin+vildagliptin+metformin.
Breast Feeding
cautionDapagliflozin+vildagliptin+metformin is generally not recommended in breastfeeding. Hence, if you are breastfeeding, inform your doctor before using Dapagliflozin+vildagliptin+metformin.
Driving
safeDapagliflozin+vildagliptin+metformin usually does not affect your ability to drive or operate machinery.
Liver
cautionUse Dapagliflozin+vildagliptin+metformin with caution, as lactic acidosis can occur due to metformin accumulation. The risk increases with hepatic insufficiency. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Kidney
cautionRenal impairment also increases the risk of lactic acidosis. Hence, Dapagliflozin+vildagliptin+metformin should be used with caution if you have kidney problems. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Children
unsafeDapagliflozin+vildagliptin+metformin is not recommended for children below 18 years as the safety and effectiveness were not established.
Habit Forming
Diet & Lifestyle Advise
- Try doing 30 minutes of moderate-intensity physical activity or one hour and 15 minutes of high-intensity exercise weekly.
- Include your diet with whole grain foods, fruits and veggies and other fiber-enriched foods.
- Add omega-3 fatty acid-containing oils for daily cooking.
- Avoid taking too much stress as it may elevate your blood sugar level. You can adopt stress management techniques like mindfulness to control stress-related blood sugar changes, meditation, or yoga.
- Loss of weight gradually to achieve a healthy body mass index (18.5 to 24.9).
- Keep your blood pressure as normal (140/90) as possible, as it reduces the risk of cardiovascular diseases in diabetes patients.
- Avoid smoking and alcohol consumption while on treatment with Dapagliflozin+vildagliptin+metformin.
- Take short, frequent meals, and avoid prolonged fasting when taking Dapagliflozin+vildagliptin+metformin.
Special Advise
- Dapagliflozin+vildagliptin+metformin may sometimes cause hypoglycemia (low blood sugar levels) as a side effect. Always carry a sugary food such as candy or fruit juice and consume them if you experience hypoglycaemia.
- Lifestyle modifications are the most important step in controlling blood sugar levels.
- Your doctor may advise frequent blood tests to check your blood sugar levels.
Patients Concern
Disease/Condition Glossary
Type II Diabetes Mellitus: It is a chronic and lifelong condition wherein the body doesn’t use insulin effectively, which causes unusual blood glucose levels. Therefore, people affected with type 2 diabetes either do not produce enough insulin or there is resistance to the action of insulin. Individuals middle-aged or older are most likely to suffer from type 2 diabetes, which is also known as adult-onset diabetes. Symptoms of type 2 diabetes include increased thirst, frequent urination at night, slow wound healing, increased hunger, fatigue, weight gain, and blurred vision.
FAQs
Dapagliflozin+vildagliptin+metformin is an antidiabetic medicine used for the treatment of Type II Diabetes.
Dapagliflozin+vildagliptin+metformin is a combination medicine containing Vildagliptin that enhances glucose-mediated insulin secretion, thereby reducing fasting and post-prandial blood sugar concentrations. Dapagliflozin helps remove excess sugar from the body via urine. Metformin helps reduce the sugar production by cells in the liver and delays sugar absorption from the intestines.
Please consult your doctor if you have concerns and for more information on this.
If you forget to take Dapagliflozin+vildagliptin+metformin, take it as soon as you remember. However, if it's time for the next dose, avoid taking it and do not double dose to make up for the missed dose. Taking an overdose might cause your sugar level to fall down rapidly.
No, Dapagliflozin+vildagliptin+metformin differs from Metformin, although both are used to treat type 2 diabetes. Dapagliflozin+vildagliptin+metformin is a combination medication containing three active ingredients: dapagliflozin, vildagliptin, and Metformin. In contrast, Metformin is a single medication and is one of the components of Dapagliflozin+vildagliptin+metformin. While Dapagliflozin+vildagliptin+metformin has a combination action, Metformin works through a single mechanism of action. Your doctor will choose the appropriate treatment based on your diabetic condition.
Dapagliflozin+vildagliptin+metformin can be taken with or without food as your doctor advises, and the timing can vary depending on individual needs. Generally, it's best to take it at the same time every day. Always follow your doctor's specific instructions regarding dosage and timing to ensure the best results.
Some individuals may experience certain side effects of Dapagliflozin+vildagliptin+metformin, such as vomiting, nausea, abdominal pain, headache, frequent urination, and allergic reactions. If these side effects persist or worsen, please consult your doctor.
Dapagliflozin+vildagliptin+metformin should be used with caution if you have kidney problems. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Dizziness is not a commonly reported side effect of Dapagliflozin+vildagliptin+metformin. However, individual responses to the medication may vary. If you experience persistent dizziness, please consult your doctor for advice and relief.
No, Dapagliflozin+vildagliptin+metformin is used to treat type 2 diabetes, not type 1 diabetes. These medications work by increasing the amounts of certain natural substances that lower blood sugar when it is high. For type 1 diabetes, different treatments are required, typically involving insulin therapy. Please consult your doctor for an appropriate treatment plan suitable for your needs.
Dapagliflozin+vildagliptin+metformin generally does not cause pancreatitis. However, individual responses to the medication may vary. If you experience symptoms such as severe abdominal pain, nausea, or vomiting while taking Dapagliflozin+vildagliptin+metformin, it's essential to seek medical attention immediately.
When taking Dapagliflozin+vildagliptin+metformin, limit or avoid excessive alcohol, high-sugar foods like candy and cakes, unhealthy fats found in fried and fast food, and processed foods like packaged snacks and frozen meals. This helps manage blood sugar levels and reduces potential side effects.
Dapagliflozin+vildagliptin+metformin is generally considered safe when used as prescribed by a doctor. However, like all medications, it can have side effects and potential interactions with other drugs. It's important to follow your doctor's instructions and inform them of any pre-existing and existing medical conditions or medication history to avoid adverse complications.
No, don’t stop taking Dapagliflozin+vildagliptin+metformin without consulting your doctor. Stopping this medication suddenly can lead to uncontrolled blood sugar levels and potential complications. It is essential to take medication as long as the doctor prescribes it to maintain blood sugar levels. Always discuss any concerns or reasons to discontinue the medication with your doctor. They will assess your health and provide suitable guidance.
Yes, proteins are necessary for people with diabetes. Protein is an essential nutrient that helps build and repair tissues and can also help manage blood sugar levels. Eat a balanced diet rich in protein and low in saturated fat, added sugars, and sodium. Consult with a registered dietitian or healthcare provider for personalized nutrition advice.
Artificial sweeteners can be a good alternative to sugar for people with diabetes, as they provide sweetness without raising blood sugar levels. If you are diabetic, consult a registered dietitian or healthcare provider for personalized advice on using artificial sweeteners.
Yes, diabetes can cause kidney failure. This condition is known as diabetic nephropathy or diabetic kidney disease. It occurs when high blood sugar levels damage the blood vessels in the kidneys, impairing their ability to filter waste and excess fluids from the body. Over time, this damage can lead to kidney failure. Controlling blood sugar levels and blood pressure and getting regular kidney check-ups can help prevent or slow kidney damage.
There is no cure for diabetes as of now. Researchers continuously explore various approaches to find a cure, including natural remedies, chemotherapy, homoeopathy, ayurveda, and allopathic medicine. However, diabetes can be managed effectively through proper diet, medication, and lifestyle changes.
No, don’t take Dapagliflozin+vildagliptin+metformin more than the prescribed dose. Taking a higher dose will not provide additional benefits and may cause adverse health complications. Following your doctor's instructions and taking Dapagliflozin+vildagliptin+metformin precisely as directed is crucial to ensure safe and effective treatment.
