Estradiol
About Estradiol
Estradiol belongs to a group of medicines called oestrogen hormones used to prevent and treat hot flashes in women experiencing menopause. It is also used to treat vaginal itching, dryness, and burning sensations in women experiencing menopause.
Estradiol contains ''estradiol'', which works by replacing the oestrogen, which is normally produced by the ovaries, thereby providing relief from menopausal symptoms.
In some cases, Estradiol may cause side effects such as headache, breast pain or tenderness, diarrhoea, gas and heartburn. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if the side effects persist or worsen.
Consult your doctor if you are pregnant, think you are pregnant, are planning for pregnancy or are breastfeeding. Avoid smoking or going near open flame until Estradiol has dried as it may catch fire. Keep your doctor informed about your health condition and medicines to rule out any side effects/interactions.
Uses of Estradiol
• Hormone Replacement Therapy: Estradiol is often used as a part of hormone replacement therapy (HRT) for women experiencing menopausal symptoms, such as hot flashes, night sweats, and vaginal dryness.
• Vaginal Atrophy Treatment: Estradiol can be used to treat vaginal atrophy, which is a common condition in postmenopausal women that leads to thinning, drying, and inflammation of the vaginal walls.
• Skin Care: Estradiol may be applied to help improve skin elasticity and hydration, especially in areas affected by hormonal changes.
• Symptomatic Relief: Estradiol is used to provide symptomatic relief in cases of hormonal imbalance that results in discomfort or other health issues associated with estrogen deficiency.
Medicinal Benefits
Estradiol belongs to a group of medicines called oestrogen hormones used to prevent and treat hot flashes in women experiencing menopause. It is also used to treat vaginal itching, dryness, and burning in women experiencing menopause. Estradiol contains ''estradiol'', which works by replacing the oestrogen, which is usually produced by the ovaries, thereby provides relief from menopausal symptoms.
Directions for Use
Storage
Side Effects of Estradiol
- Headache
- Breast tenderness or pain
- Diarrhoea
- Gas
- Heartburn
Drug Warnings
Do not use Estradiol if you are allergic to any of its components. Inform your doctor if you have/had a hysterectomy (surgery to remove the uterus), abnormal or unusual vaginal bleeding, heart attack, stroke, breast cancer, blood clots, high blood pressure, high cholesterol or fat, diabetes, heart disease, breast lumps, lupus (the body attacks its own tissues causing damage and swelling), asthma, migraine headache, seizures, uterine fibroids (growths in the uterus that are non-cancerous), endometriosis (growth of the womb lining outside the womb), yellowing of the skin and eyes, very high/low levels of calcium, gallbladder, pancreas, thyroid, liver or kidney problems, porphyria (a condition in which abnormal substances build up in the blood and cause problems with the skin or nervous system) or if you smoke.
Drug Interactions
Drug-Drug Interactions: Inform your doctor if you are taking anti-fungal (itraconazole, ketoconazole), anti-convulsant (carbamazepine, phenobarbital), antibiotic (clarithromycin, erythromycin, rifampin), statins (lovastatin), anti-retroviral (ritonavir), medicines for thyroid disease, and herbal supplement (St. John's wort).
Drug-Food Interactions: No interactions found.
Drug-Disease Interactions: Inform your doctor if you have/had a heart attack, stroke, abnormal/unusual vaginal bleeding, breast cancer, or blood clots.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
consult your doctorIt is not known if alcohol interacts with Estradiol. Consult your doctor if you have any concerns.
Pregnancy
cautionConsult your doctor if you are pregnant or planning pregnancy before using Estradiol.
Breast Feeding
cautionIf you are breastfeeding, consult your doctor before using Estradiol.
Driving
safeEstradiol does nor affect your ability to drive.
Liver
consult your doctorPlease consult your doctor if you have a liver impairment or any concerns before using Estradiol.
Kidney
consult your doctorPlease consult your doctor if you have kidney impairment or any concerns before using Estradiol.
Children
consult your doctorLimited information is available. Please consult your doctor.
Habit Forming
Diet & Lifestyle Advise
- Include foods such as soybeans, flax seeds, and soy products in your diet.
- Maintain a healthy weight by exercising regularly. Also, avoid exercising too much. Do it moderately.
- Drink plenty of water to stay hydrated.
- Try to limit alcohol and caffeine.
- Choose personnel care items that are pH balanced.
Special Advise
- Do not let anyone touch the skin where you have applied Estradiol for one hour. In case of accidental contact, ask them to wash immediately with soap.
- Make sure that the skin where you will apply Estradiol is clean and completely dry.
- Regular breast examinations and mammogram tests are recommended.
- Avoid contact of Estradiol with eyes; wash with plenty of water if contact occurs. Consult your doctor if you experience eye irritation.
- Consult your doctor immediately if you experience any of these symptoms: sudden, severe vomiting; sudden, severe headache; dizziness or faintness; speech problems; sudden complete or partial loss of vision; weakness or numbness of an arm or a leg; double vision; crushing chest pain or chest heaviness; breast lumps or other breast changes; discharge from nipples; coughing up blood; difficulty thinking clearly, remembering, or learning new things; sudden shortness of breath; or pain, tenderness, or redness in one leg.
Patients Concern
Disease/Condition Glossary
Menopausal symptoms: Menopause is a condition in which a woman hasn’t had periods for 12 consecutive months. It usually begins between the ages of 45-55 years. Symptoms include hot flashes, vaginal itching, irritation, dryness, and a burning sensation. They occur due to a drop in the levels of oestrogen that naturally happens after menopause.
FAQs
Estradiol is used to treat postmenopausal symptoms such as hot flashes, vaginal itching, dryness, and burning sensation.
Estradiol works by replacing the oestrogen, which is generally produced by the ovaries. Thus, it provides relief from menopausal symptoms.
If you take a bath/shower or use a sauna, apply Estradiol after you have finished bathing/showering or using the sauna and have dried the skin completely.
Avoid unnecessary/prolonged exposure to sunlight as Estradiol may make your skin sensitive to sunlight. Wear protective clothing, sunglasses, and sunscreen. However, do not apply sunscreen before, during, or after applying Estradiol. Maintain a gap of some time between applying Estradiol and sunscreen.
