Faricimab
About Faricimab
Faricimab belongs to the class of anti-angiogenic ophthalmic agents, used to improve and maintain vision in diabetic macular edema (DME), neovascular (wet) age-related macular degeneration (nAMD), or macular edema following retinal vein occlusion (RVO) in adults. Neovascular (wet) age-related macular degeneration (nAMD), diabetic macular edema (DMO), and retinal vein occlusion (RVO) are chronic eye conditions characterized by the growth of abnormal blood vessels beneath the retina and macula, leading to fluid accumulation, swelling, and vision impairment.
Faricimab contains Faricimab, which works by blocking the activity of proteins known as angiopoietin-2 and vascular endothelial growth factor A. Excessive levels of these proteins can cause abnormal blood vessel growth, damaging normal vessels and leading to retinal leakage, swelling, and vision problems in conditions like nAMD, DMO, and RVO. By attaching to these proteins, Faricimab blocks their actions and prevents abnormal vessel growth, leakage, and swelling. Faricimab can prevent further damage, slow disease progression, and potentially improve vision.
A healthcare professional will administer Faricimab. The common side effects of Faricimab include conjunctival hemorrhage (blood in the white part of the eye), intraocular pressure, eye pain, intraocular inflammation or irritation, blurred vision and increased lacrimation. Most of these adverse effects go away gradually over time on their own. If any of these symptoms worsen or continue, consult a doctor.
Faricimab should be avoided if you are allergic to it or any other components present in it. Before receiving Faricimab, inform your doctor if you have any liver or kidney disease, ocular or periocular infection and active intraocular inflammation. Pregnant and breastfeeding mothers should inform the physician before starting treatment with Faricimab.
Uses of Faricimab
Medicinal Benefits
Faricimab contains Faricimab, which works by blocking the activity of proteins known as angiopoietin-2 and vascular endothelial growth factor A. Excessive levels of these proteins can cause abnormal blood vessel growth, damaging normal vessels and leading to retinal leakage, swelling, and vision problems in conditions like nAMD, DMO, and RVO. By attaching to these proteins, Faricimab can block their actions and prevent abnormal vessel growth, leakage, and swelling. Faricimab can prevent further damage, slow disease progression, and potentially improve vision.
Directions for Use
Storage
Side Effects of Faricimab
- Conjunctival hemorrhage (blood in the white part of the eye)
- Intraocular pressure
- Eye pain
- Intraocular inflammation or irritation
- Blurred vision
- Increased lacrimation.
Drug Warnings
Faricimab should be avoided if you allergic to it or any other components present in it. Before receiving Faricimab, inform your doctor if you have any liver or kidney disease, ocular or periocular infection and active intraocular inflammation. Pregnant and breastfeeding mothers should inform the physician before starting treatment with Faricimab.
Drug Interactions
Drug-Drug Interaction: No interactions found.
Drug-Food Interaction: No interactions found.
Drug-Disease Interaction: Faricimab should be used with caution in cases of liver or kidney diseases, ocular or periocular infection and active intraocular inflammation.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
consult your doctorIt is not known whether Faricimab interacts with alcohol. Please consult your doctor.
Pregnancy
consult your doctorIf you are pregnant or planning to become pregnant, inform your doctor before receiving Faricimab. Your doctor may recommend Faricimab if the potential benefits outweigh the possible risks.
Breast Feeding
consult your doctorIt is unknown whether Faricimab passes into breast milk. If you are breastfeeding or plan to breastfeed, please consult your doctor before receiving it.
Driving
cautionFaricimab may cause blurred vision. Therefore, avoid driving or operating machinery until your vision is clear.
Liver
consult your doctorPlease inform your doctor if you have liver impairment/liver disease before receiving Faricimab.
Kidney
consult your doctorPlease inform your doctor if you have kidney impairment/kidney disease before receiving Faricimab.
Children
consult your doctorThe safety and effectiveness of Faricimab in children have not been established. Please consult your doctor if you have any concerns regarding use of Faricimab for children.
Habit Forming
Diet & Lifestyle Advise
- Eat a nutritious, well-balanced diet to support your overall well-being.
- Quit smoking and limit consumption of alcohol to reduce health risks.
- Reduce intake of salty, sugary, and processed foods.
- Create a healthier home environment by minimizing exposure to allergens like pollen, dust mites, and pet dander. Regular cleaning and using air purifiers can be beneficial.
- Drink lots of water throughout the day to stay hydrated.
Patients Concern
Disease/Condition Glossary
Neovascular (wet) age-related macular degeneration (nAMD): Wet age-related macular degeneration (nAMD) is a chronic eye condition where abnormal blood vessels grow under the retina, causing fluid leaks, swelling, and vision loss. Age, genetics, and smoking contribute to its development. Symptoms include blurred vision, distorted lines, and dark spots.
Diabetic macular edema (DME): Diabetes macular edema (DME) is swelling in the macula, or central, part of the retina of eye. It occurs when high blood sugar levels affect the blood vessels in eyes causing fluid leakage into the macula. This leads to symptoms such as blurred or distorted vision, dark spots, and difficulty distinguishing colors.
Macular edema following retinal vein occlusion (RVO): Retinal vein occlusion (RVO) is a partial or total blockage in a vein that drains blood from retina, certain health conditions, such as high blood pressure, diabetes, or heart problems, can cause vision problems. Symptoms may include dark spots, blurry or distorted vision, and gradual vision loss.
FAQs
Faricimab is an anti-angiogenic ophthalmic agent used to improve and maintain vision in neovascular (wet) age-related macular degeneration (nAMD), diabetic macular edema (DME), or macular edema following retinal vein occlusion (RVO) in adults.
Faricimab contains Faricimab, which works by blocking angiopoietin-2 and vascular endothelial growth factor A (VEGF-A), thereby reducing the abnormal blood vessel growth and damage to normal vessels. This helps manage conditions like neovascular (wet) age-related macular degeneration (nAMD), diabetic macular edema (DME), or macular edema following retinal vein occlusion (RVO) effectively.
Please inform your doctor before taking other medicines while being treated with Faricimab. Your doctor will determine which medicines should not be taken along with Faricimab.
Store Faricimab in a refrigerator between 2ºC to 8ºC. Do not freeze. Do not shake. Keep out of reach of children.
The common side effects of Faricimab are conjunctival hemorrhage (blood in the white part of the eye), intraocular pressure, eye pain, intraocular inflammation or irritation, blurred vision and increased lacrimation. If any of these side effects persist or worsen, please consult your doctor.
Available Medicines for
Faricimab
Vabysmo 6 mg (0.05 ml of 120mg/ml Solution) Injection 1's
1 Vial
₹60183.9 (MRP 73395)18%Off
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