FLUPIRTINE+PARACETAMOL is a combination medication that belongs to the analgesic medication class. It is widely used in the treatment of acute and chronic pain, fever, headache, joint pains, dysmenorrhea (period pain), postoperative pain, toothache after dental extraction, and myalgia (muscle pain). Pain is a widely used term used to describe an unpleasant feeling or discomfort. It ranges from mild to severe. The severity of the pain depends on the underlying condition. Inflammation is the immune system's natural response to injury or infection.
FLUPIRTINE+PARACETAMOL contains flupirtine and paracetamol. Flupirtine is an analgesic (non-opioid analgesic) which works by blocking the transmission of pain signals to the brain to lower pain perception. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer), which works by blocking the release of certain chemical messengers that cause fever and pain. Thus FLUPIRTINE+PARACETAMOL alleviates pain and other associate conditions.
Use FLUPIRTINE+PARACETAMOL as directed by the physician only. The dose and duration of the medication depend on your condition and its severity. The common side effects of FLUPIRTINE+PARACETAMOL include nausea, vomiting, wind, abdominal discomfort, diarrhoea, constipation, heartburn, drowsiness, dizziness, headache, and depression. Most of these side effects of FLUPIRTINE+PARACETAMOL are temporary, do not require medical attention, and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
Before taking FLUPIRTINE+PARACETAMOL, inform your doctor if you are allergic to flupirtine, paracetamol, or other ingredients. Besides, inform your doctor if you are pregnant, breastfeeding, or have any pre-existing conditions such as liver diseases such as hepatic encephalopathy (loss of brain function due to liver damage), chronic alcoholism, or cholestasis (reduced bile flow), renal impairment, myasthenia gravis (chronic neuromuscular disease), or heart diseases. If FLUPIRTINE+PARACETAMOL is given in patients with liver diseases, liver function should be monitored closely. FLUPIRTINE+PARACETAMOL causes drowsiness and dizziness, so drive only if you are alert. FLUPIRTINE+PARACETAMOL is not recommended for children younger than six years old.
Pain relief
FLUPIRTINE+PARACETAMOL contains flupirtine (non-opioid analgesic) and paracetamol (analgesic and antipyretic). Flupirtine works by blocking the glutamate receptors that are involved in producing pain signals. It also has muscle relaxant properties. Paracetamol acts as an analgesic and antipyretic by inhibiting the release of prostaglandins (chemical mediators) that cause pain, inflammation, and fever. Altogether provide relief from pain and associated symptoms.
Avoid using FLUPIRTINE+PARACETAMOL if you are allergic to analgesics or painkillers. People with liver diseases, kidney diseases, and elderly people above 65 years of age may require dose adjustments. If FLUPIRTINE+PARACETAMOL is given to patients with liver impairment, liver function should be closely monitored. It is advised to discontinue use if you notice any signs of liver damage such as nausea, vomiting, yellowed skin and eyes (jaundice), abdominal pain, loss of appetite, itchy skin, and dark-coloured urine, etc.
Drug-drug interactions: FLUPIRTINE+PARACETAMOL may interact with anticoagulants such as warfarin.
Drug-food interactions: The use of alcohol with FLUPIRTINE+PARACETAMOL is restricted as alcohol may worsen the side effects of the medicine.
Drug-disease interactions: FLUPIRTINE+PARACETAMOL should not be given in patients with alcoholism, liver disease and phenylketonuria (excess of protein – phenylalanine in the body).
Consuming alcohol with FLUPIRTINE+PARACETAMOL is not advisable as it may cause unpleasant side effects, or you may become more sensitive to the effects of alcohol.
FLUPIRTINE+PARACETAMOL is not recommended during pregnancy. However, your doctor may prescribe it for you during pregnancy if he/she feels the benefit outweighs the risk.
According to the studies available to date, a small percentage of flupirtine maleate passes into breast milk. Therefore, flupirtine maleate must not be administered during lactation unless necessary.
Avoid driving or operating heavy machinery after taking FLUPIRTINE+PARACETAMOL, as it may cause dizziness.
FLUPIRTINE+PARACETAMOL can cause liver toxicity. So, it should be avoided in patients with liver diseases. However, dose adjustments and close monitoring are necessary if it is used in patients with liver diseases.
In patients with kidney problems, dose adjustments of FLUPIRTINE+PARACETAMOL are required. Therefore, use FLUPIRTINE+PARACETAMOL only when prescribed by a doctor.
It is recommended to consult a doctor before using FLUPIRTINE+PARACETAMOL in children below six years.
Pain is a widely used term used to describe an unpleasant feeling or discomfort. It ranges from mild to severe. The severity of the pain depends on the underlying condition. It is also classified as acute (short-term) and chronic (long-term), depending on the duration of the pain. Acute pain, if left untreated, can result in chronic pain in some conditions.