Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide
About Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide
Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide is used in the treatment of patients with chronic obstructive pulmonary disease to relieve symptoms and prevent exacerbations. COPD is a group of lung diseases that includes emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of the bronchial tubes).
Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide contains Budesonide, glycopyrrolate, and formoterol fumarate dihydrate. Formoterol fumarate works by relaxing muscles and widening the lungs' airways. Glycopyrrolate reduces secretions in the airways. Budesonide acts on nasal lining cells and prevents the release of inflammatory mediators.
Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide may cause specific side effects, including oral thrush, cough, difficulty breathing, chills, back pain, muscle spasms, low blood pressure, nausea, and vomiting. Inform your doctor if these side effects persist or worsen.
Inform your doctor if you are allergic to Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide. Before taking Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide, let your doctor know if you have any history of liver/kidney disease, glaucoma, asthma, heart disease, paradoxical bronchospasm, hypokalemia, or hyperglycaemia. If you are pregnant or breastfeeding, please inform your doctor before using Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide.
Uses of Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide
Medicinal Benefits
- Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide is a combination inhalation therapy that contains budesonide (an inhaled corticosteroid), glycopyrronium, and formoterol (a long-acting beta-2 adrenergic agonist).
- This combination offers both anti-inflammatory and bronchodilator actions, providing comprehensive control over respiratory conditions such as Asthma and Chronic Obstructive Pulmonary Disease (COPD).
- Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide is used as a regular maintenance therapy for individuals with asthma where the use of inhaled corticosteroids and long-acting beta-agonists (LABA) is appropriate.
- It reduces airway inflammation and prevents bronchospasm, thereby minimising the frequency and severity of asthma attacks.
- Helps maintain long-term asthma control, improves lung function, and enhances quality of life.
- Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide is also indicated for the regular treatment of moderate to severe COPD in patients who experience frequent symptoms and have a history of exacerbation.
- Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide decreases the rate and severity of COPD exacerbations and maintains day-to-day function.
Directions for Use
- Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
- Place the mouthpiece between your lips, press the inhaler, and breathe in slowly. Hold your breath for a few seconds, then slowly breathe out.
- Always shake the container for 5 seconds before each use.
- Rinse your mouth with water and spit it out after using it to help prevent fungal infections in your mouth and throat.
Storage
Side Effects of Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide
- Headache
- Oral thrush
- Nausea
- Vomiting
- Upper respiratory tract infections
- Cough
- Difficulty breathing
- Hypotension
- Feeling tired
- Diarrhoea
- Back pain
- Muscle spasms
Drug Warnings
- Discontinue the medicine and inform your doctor if you observe any allergic reactions or are known allergic to any ingredients.
- This medicine is contraindicated for use in asthma patients, acute episodes of COPD, and use of other LABA drugs, as it can cause serious side effects.
- Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide may cause glaucoma, oropharyngeal candidiasis, adrenal suppression, cardiovascular effects, paradoxical bronchospasm, serious anaphylactic reactions, hypokalaemia, hyperglycaemia, pneumonia and deterioration of disease.
- Inform your doctor if you have any conditions like liver/kidney disease, glaucoma, asthma, heart disease, seizures, weak immune system, osteoporosis, diabetes, thyroid disorders, prostate/bladder problems, a serious infection, or medication history of anticholinergics, atropine, other LABA drugs, antifungal or anti-HIV medicines if you are pregnant or breastfeeding, please inform your doctor before using Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide.
- Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide is not recommended for children as the safety is not established.
- This medicine may cause harm to the developing baby. Hence, it is advised to inform your doctor if you are pregnant or breastfeeding before starting the treatment.
Drug Interactions
Drug-Drug Interactions: Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide may interact with other long-acting bronchodilators (salbutamol, vilanterol, olodaterol, indacaterol), anticholinergic drugs (ipratropium, tiotropium, aclidinium), medicines to induce labour (oxytocin), antithyroid agent (levothyroxine), antidepressants (imipramine, amitriptyline, isocarboxazid, phenelzine), antifungals (itraconazole, ketoconazole), HIV medicines (atazanavir, ritonavir, nelfinavir, indinavir, cobicistat, saquinavir), etc.
Drug-Food Interactions: Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide may interact with grapefruit and grapefruit juice. Therefore, avoid consuming grapefruit or its juice with Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide as it may lead to severe adverse effects. Also, it is safe to limit alcohol and caffeine intake.
Drug-Disease Interactions: Inform your doctor if you have low blood pressure, diabetes, hypokalaemia, glaucoma, osteoporosis, heart, liver, or adrenal gland problems before taking Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
consult your doctorThe interaction of Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide with alcohol is unknown. Discuss with your doctor if you have any concerns.
Pregnancy
unsafeFormoterol Fumarate Dihydrate+glycopyrrolate+budesonide is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before taking Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide. Your doctor may prescribe this medicine if the benefits outweigh the risks.
Breast Feeding
consult your doctorLimited data is available on the effect of Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide in breastfeeding. Hence, if you are a nursing mother, inform your doctor before receiving Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide. Your doctor may prescribe this medicine if the benefits outweigh the risks.
Driving
safe if prescribedFormoterol Fumarate Dihydrate+glycopyrrolate+budesonide usually does not affect your ability to drive or operate machinery.
Liver
cautionSince the liver is the primary organ responsible for the elimination of budesonide and formoterol, patients with severe liver impairment may be more exposed. Hence, use Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide with caution if you have liver disease.
Kidney
consult your doctorLimited data is available. Please consult your doctor for more information.
Children
unsafeFormoterol Fumarate Dihydrate+glycopyrrolate+budesonide is not recommended for use in children as the safety and efficacy have not been established.
Habit Forming
Diet & Lifestyle Advise
- Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.
- Learning breathing exercises will help you move more air in and out of your lungs.
- Do meditation, deep breathing, regular exercise, and try progressive muscle relaxation techniques to get relief from stress and reduce the risk of an asthma attack.
- Quit smoking as it may reduce the effectiveness of the Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide and irritate the lungs, worsening breathing problems.
Special Advise
- Regular blood sugar levels and blood pressure monitoring are recommended while taking Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide.
- Your doctor may also suggest a blood test of the liver/kidney and CBC to check for any abnormalities in the results.
Patients Concern
Disease/Condition Glossary
Chronic obstructive pulmonary disease (COPD): It is a group of lung diseases characterised by emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of the bronchial tubes). The primary cause of COPD is smoking tobacco. Also, long-term exposure to fumes and chemicals may lead to COPD. The symptoms include chronic cough, shortness of breath, or wheezing (whistle sound while breathing).
FAQs
Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide is used as a maintenance treatment in patients with chronic obstructive pulmonary disease (COPD).
Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide works by relaxing muscles and widening the airways of the lungs. Also, it stops the release of certain chemicals in the body that cause inflammatory reactions.
You are not recommended to take more than the prescribed dose of Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide as it may cause adverse effects such as muscle cramps, headache, high or low blood pressure, fits, severe chest pain, dry mouth, difficulty in sleeping, or light-headedness. However, if you experience these symptoms while taking Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide, please consult a doctor immediately.
No, it is always advised not to stop taking the medicine even if your condition improves, as it may worsen or cause recurring symptoms. If you feel better, inform your doctor before you stop taking Formoterol Fumarate Dihydrate+glycopyrrolate+budesonide. Your doctor will decide whether to stop or not based on your symptoms.
