Glycerin+mannitol
About Glycerin+mannitol
Glycerin+mannitol is a medication used to treat cerebral oedema (brain swelling). It is also used to prevent and treat the oliguric phase of acute renal failure before irreversible renal failure is established. Cerebral oedema is the medical term for brain swelling, or swelling that happens in part or all of the brain because of excessive fluid buildup in the tissue. Acute renal failure (also known as acute kidney injury) is a sudden loss of kidney function that occurs over a short period, usually within a few hours or days.
Glycerin+mannitol contains glycerine and mannitol as its active components, which work to reduce brain swelling by drawing out excess fluid, lowering brain pressure, and helping the brain function properly. Additionally, Glycerin+mannitol increases urine flow to remove excess fluid and support kidney function, helping to prevent long-term brain and kidney damage.
Glycerin+mannitol will be administered by a healthcare professional; do not self-administer. Common side effects of Glycerin+mannitol include injection site reactions, hypotension, difficulty breathing, skin rash, and hives. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, inform your doctor.
Let your doctor know about your medical condition and the medications you are taking to avoid the occurrence of potential interactions. Inform your doctor if you are pregnant, breastfeeding, suspect you are pregnant or plan to have a baby; your doctor will weigh the benefits of Glycerin+mannitol therapy against the risks. Consumption of alcohol should be avoided while on treatment with Glycerin+mannitol.
Uses of Glycerin+mannitol
Prevention and Treatment of Acute Renal Failure: Glycerin+mannitol helps prevent and treat the oliguric phase of acute renal failure by increasing the flow of urine and removing excess fluid from the body.
Medicinal Benefits
Glycerin+mannitol is used to treat brain swelling (cerebral edema) by removing excess fluid from the brain. The ingredients mannitol and glycerine help draw fluid out of the brain and into the bloodstream, which lowers pressure, reduces swelling, and allows the brain to function properly. This process helps prevent long-term brain damage. Additionally, Glycerin+mannitol is beneficial in preventing and treating the oliguric phase of acute renal failure by increasing urine flow and removing excess fluid from the body. This helps support kidney function, prevent fluid buildup, and reduce the risk of further kidney damage.
Directions for Use
Storage
Side Effects of Glycerin+mannitol
- Injection site reactions
- Hypotension
- Difficulty breathing
- Skin rash
- Hives
Drug Warnings
Before starting treatment with Glycerin+mannitol, inform your doctor if you are allergic to any of its active ingredients and provide a complete list of your medical conditions and medications to avoid potential interactions. If you are pregnant, planning to become pregnant, or breastfeeding, let your doctor know so they can assess the risks and benefits of using Glycerin+mannitol. Be cautious when using Glycerin+mannitol with other medications or vaccines. If you experience any side effects that persist or worsen, inform your doctor and seek appropriate medical attention.
Drug Interactions
Drug-Drug Interaction: No specific interactions found.
Drug-Food Interaction: No specific interactions found.
Drug-Disease Interaction: No specific interactions found.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionIt is not known whether it is safe to consume alcohol with Glycerin+mannitol. However, as a precautionary measure, it is advisable not to drink or limit alcohol.
Pregnancy
cautionLimited data is available. If you are pregnant or planning to become pregnant, inform your doctor before receiving Glycerin+mannitol. Your doctor may prescribe this medicine if the benefits outweigh the risks.
Breast Feeding
cautionInform your doctor if you are breastfeeding. When deciding whether to discontinue nursing or the medicine, consider the importance of the treatment to the mother.
Driving
cautionIt is unclear whether Glycerin+mannitol affects your ability to drive. If you suspect any difficulty, refrain from driving or operating machinery.
Liver
cautionLimited information is available about using Glycerin+mannitol in patients with liver disease. If you have a history of liver disease, inform your doctor before receiving Glycerin+mannitol. Your doctor will prescribe it only if the benefits outweigh the risks.
Kidney
cautionLimited information is available about using Glycerin+mannitol in patients with kidney disease. If you have a history of kidney disease, inform your doctor before receiving Glycerin+mannitol. Your doctor will prescribe it only if the benefits outweigh the risks.
Children
cautionThere was limited information about the usage of Glycerin+mannitol in paediatric patients. Please seek medical advice. Your doctor may prescribe this medicine if the benefits outweigh the risks.
Habit Forming
Diet & Lifestyle Advise
- Reduce sodium intake to prevent fluid retention and manage blood pressure.
- Monitor fluid intake carefully to avoid dehydration and excessive buildup.
- Eat potassium-rich foods like bananas and spinach to maintain electrolyte balance.
- Limit high-protein foods to reduce waste products and prevent kidney strain.
- Cut back on salt and processed foods to minimize kidney strain.
- Choose foods low in potassium, phosphorus, and sodium to support kidney function.
- Stay hydrated with the right amount of fluids, avoiding overhydration.
- Maintain a healthy lifestyle with controlled physical activity and proper management of conditions like hypertension and diabetes.
Patients Concern
Disease/Condition Glossary
Cerebral edema: This is a life-threatening condition characterized by fluid accumulation in the brain, which increases pressure and can lead to severe symptoms and complications. Causes include head trauma, stroke, infections, tumors, and metabolic disorders. Symptoms can vary from headaches and nausea to seizures, coma, and even death. Treatment focuses on reducing pressure with medications such as mannitol, steroids, and possibly surgery, while also addressing the underlying cause. If untreated, cerebral edema can result in brain damage or fatal outcomes.
Acute renal failure: It is a sudden loss of kidney function, often caused by reduced blood flow, damage, or blockages. Dehydration, heart failure, infections, toxins, or kidney stones can trigger it. Symptoms include low urine output, swelling, fatigue, confusion, and nausea. High-risk groups include those with pre-existing kidney disease, diabetes, hypertension, older adults, and users of certain medications. Prompt treatment is crucial to prevent further complications.
FAQs
Glycerin+mannitol is used to treat brain swelling (cerebral edema) and prevent or treat the oliguric phase of acute renal failure.
Glycerin+mannitol contains glycerine and mannitol as its active components. It enhances blood osmolarity, facilitating the transfer of excess fluid from brain tissue to the bloodstream. This process effectively reduces intracranial pressure, reducing cerebral edema and associated complications. The excess liquid is then eliminated through osmotic diuresis, further reducing swelling. Promoting fluid removal helps restore normal brain function and mitigate potential long-term damage.
Glycerin+mannitol causes side effects such as injection site reactions, hypotension, difficulty breathing, skin rash, and hives. Therefore, contact a doctor if these side effects persist or worsen.
Glycerin+mannitol is a parenteral therapy administered by a healthcare professional. The appropriate dose is carefully determined and given based on individual patient needs. Using more than the recommended dose is not recommended, as it can increase the risk of serious side effects
As Glycerin+mannitol is a parenteral formulation, you will usually receive it through an injection or IV infusion in a healthcare setting, under the supervision of a doctor. Please contact your doctor if you have any further concerns.
Before taking the Glycerin+mannitol, let your doctor know about all your medical conditions, sensitivities, and all medications you are using.
Glycerin+mannitol contains mannitol and glycerine as its active ingredients.
The length of treatment will depend on your specific condition. Your doctor will determine the best course of treatment for you.
If you are pregnant or breastfeeding, please inform your doctor before using Glycerin+mannitol. Your doctor will help you weigh the benefits and risks to ensure your safety and the safety of your baby.
