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Human Papillomavirus Bivalent Vaccine Recombinant

About Human Papillomavirus Bivalent Vaccine Recombinant

Human Papillomavirus Bivalent Vaccine Recombinant belongs to the class of medicines called ‘immunizing agents’ used in females over 9 to 25 years of age to prevent cervical cancer and precancerous lesions in the genital area (cervix, vulva, vagina or anus). It protects against the diseases caused by oncogenic human papillomavirus (HPV) types 16 and 18, including cervical cancer, cervical intraepithelial neoplasia (CIN) grades 2 or worse, adenocarcinoma in situ (early-stage cancer cells that are confined to the lining of the cervix), and cervical intraepithelial neoplasia (CIN) grade 1. Cervical cancer is a cancer that occurs in the cells of the cervix, which is the lower part of the uterus connecting to the vagina. Caused by exposure to specific high-risk human papillomavirus (HPV) strains. Symptoms include vaginal bleeding, unusual discharge, and pain in the lower back, between hip bones (pelvis), or in the lower tummy.

Human Papillomavirus Bivalent Vaccine Recombinant contains proteins of human papillomavirus (HPV) types 16 and 18 in the form of non-infectious virus-like particles (VLPs). It stimulates the body's immune response, resulting in the generation of antibodies against HPV types 16 and 18. This immune response helps prevent HPV infection and reduces the risk of HPV-related diseases, including cervical cancers.

Human Papillomavirus Bivalent Vaccine Recombinant will be administered by a healthcare professional. In a few cases, Human Papillomavirus Bivalent Vaccine Recombinant may cause side effects such as fever, nausea, vomiting, diarrhoea, headache, tiredness, myalgia (muscle pain), arthralgia (pain in one or more joints), stomach pain, and redness, pain, and swelling at the injection site. These side effects are temporary and resolve without any treatment. However, inform your doctor immediately if any of these side effects persist or get worse.  

Before taking Human Papillomavirus Bivalent Vaccine Recombinant, please inform your doctor if you are allergic to Human Papillomavirus Bivalent Vaccine Recombinant. Let your doctor know if you are pregnant, think you may be pregnant or plan to have a baby or breastfeed. Keep your doctor informed about your health condition and all the medicines you take before taking Human Papillomavirus Bivalent Vaccine Recombinant to rule out any side effects. Human Papillomavirus Bivalent Vaccine Recombinant should not be used in children under nine, as its safety and effectiveness are not confirmed for this age group.

Uses of Human Papillomavirus Bivalent Vaccine Recombinant

Human Papillomavirus Bivalent Vaccine Recombinant is used in females over 9 to 25 years of age to prevent cervical cancer and precancerous lesions in the genital area (cervix, vulva, vagina or anus). It protects against the diseases caused by oncogenic human papillomavirus (HPV) types 16 and 18, including cervical cancer, cervical intraepithelial neoplasia (CIN) grades 2 or worse, adenocarcinoma in situ (early-stage cancer cells that are confined to the lining of the cervix), and cervical intraepithelial neoplasia (CIN) grade 1.

Medicinal Benefits

Human Papillomavirus Bivalent Vaccine Recombinant is used in females over 9 to 25 years of age to prevent cervical cancer and precancerous lesions in the genital area (cervix, vulva, vagina or anus). It protects against the diseases caused by oncogenic human papillomavirus (HPV) types 16 and 18, including cervical cancer, cervical intraepithelial neoplasia (CIN) grades 2 or worse, adenocarcinoma in situ (early-stage cancer cells that are confined to the lining of the cervix), and cervical intraepithelial neoplasia (CIN) grade 1.

Directions for Use

• Human Papillomavirus Bivalent Vaccine Recombinant is administered in a series of 3 doses according to the following schedule: 0, 1, and 6 months or as advised by the doctor. • Human Papillomavirus Bivalent Vaccine Recombinant is administered by the doctor or nurse in a healthcare setting. • Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Human Papillomavirus Bivalent Vaccine Recombinant

  • Redness, pain, and swelling at the injection site
  • Fever
  • Nausea
  • Vomiting
  • Diarrhoea
  • Headache
  • Tiredness
  • Myalgia (muscle pain)
  • Arthralgia (pain in one or more joints)
  • Stomach pain

Drug Warnings

Before taking Human Papillomavirus Bivalent Vaccine Recombinant, please inform your doctor if you are allergic to Human Papillomavirus Bivalent Vaccine Recombinant. Let your doctor know if you are pregnant or breastfeeding, think you may be pregnant or plan to have a baby. Keep your doctor informed about your health condition and all the medicines you take before taking Human Papillomavirus Bivalent Vaccine Recombinant to rule out any side effects. Human Papillomavirus Bivalent Vaccine Recombinant should not be used in children under nine, as its safety and effectiveness are not confirmed for this age group.

Drug Interactions

Drug-Drug Interactions: Human Papillomavirus Bivalent Vaccine Recombinant may interact with immunosuppressants (abatacept, Abrocitinib and Anti-thymocyte globulin), monoclonal antibodis (Anifrolumab), corticosteroids (Hydrocortisone), anticancer medications (Bleomycin, Abemaciclib).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Inform your doctor if you have any liver or kidney diseases before receiving Human Papillomavirus Bivalent Vaccine Recombinant.

Drug-Drug Interactions Checker List:

  • ABATACEPT
  • ABROCITINIB
  • ABEMACICLIB
  • HYDROCORTISONE
  • BLEOMYCIN
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      It is unknown whether it is safe to consume alcohol with Human Papillomavirus Bivalent Vaccine Recombinant. However, it is advisable not to take or limit alcohol as a precautionary measure.

    • Safety Warning

      Pregnancy

      caution

      Please consult the doctor. There are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe Human Papillomavirus Bivalent Vaccine Recombinant only if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      There is limited data on the use of Human Papillomavirus Bivalent Vaccine Recombinant during breastfeeding. Consult your healthcare provider to assess risks and benefits.

    • Safety Warning

      Driving

      safe if prescribed

      Human Papillomavirus Bivalent Vaccine Recombinant may not affect your ability to drive.

    • Safety Warning

      Liver

      consult your doctor

      Consult your doctor if you have liver impairment. Your doctor will weigh the benefits and any potential risks before prescribing.

    • Safety Warning

      Kidney

      consult your doctor

      Consult your doctor if you have kidney impairment. Your doctor will weigh the benefits and any potential risks before prescribing.

    • Safety Warning

      Children

      caution

      Human Papillomavirus Bivalent Vaccine Recombinant should not be used in children under nine years.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Consume a healthy diet rich in fruits, vegetables, whole grains, and lean proteins. Avoid processed and refined foods.
    • Eat foods rich in vitamin C such as tomatoes, strawberries, and citrus fruits help to improve immunity. 
    • Limit dairy products such as milk and cheese.
    • Limit alcohol and caffeine intake and quit smoking.
    • Take adequate bed rest.
    • Drink a lot of water. Staying hydrated is essential both before and after your vaccination.
    • Eat a well-balanced diet. A well-balanced diet is essential.

    Special Advise

    Human Papillomavirus Bivalent Vaccine Recombinant may cause syncope (temporary loss of consciousness), which can lead to a fall with injuries, therefore, it is recommended to observe the patient for 15 minutes following the injection.

    Patients Concern

    Disease/Condition Glossary

    Cervical cancer: Cervical cancer is a cancer that occurs in the cells of the cervix, which is the lower part of the uterus connecting to the vagina. It is caused by exposure to specific high-risk human papillomavirus (HPV) strains. Symptoms include vaginal bleeding, unusual discharge, and pain in the lower back, between hip bones (pelvis), or in the lower tummy.

    FAQs

    Human Papillomavirus Bivalent Vaccine Recombinant is used in females over 9 to 25 years of age to prevent cervical cancer and precancerous lesions in the genital area (cervix, vulva, vagina or anus). It protects against the diseases caused by oncogenic human papillomavirus (HPV) types 16 and 18, including cervical cancer, cervical intraepithelial neoplasia (CIN) grades 2 or worse, adenocarcinoma in situ (early-stage cancer cells that are confined to the lining of the cervix), and cervical intraepithelial neoplasia (CIN) grade 1.

    Human Papillomavirus Bivalent Vaccine Recombinant contains human papillomavirus (HPV) bivalent type 16 type 18. It stimulates the body's immune response, resulting in the generation of of antibodies against HPV types 16 and 18. This immune response helps prevent HPV infection and reduces the risk of HPV-related diseases, including cervical cancers.

    The common side effects of Human Papillomavirus Bivalent Vaccine Recombinant are fever, nausea, vomiting, diarrhoea, headache, tiredness, myalgia (muscle pain), arthralgia (pain in one or more joints), stomach pain, and redness, pain, and swelling at the injection site. If any of these side effects persist or worsen, contact your doctor right away.

    There are no adequate and well-controlled studies on pregnant and nursing women. Inform your doctor before receiving Human Papillomavirus Bivalent Vaccine Recombinant. If you are pregnant or breastfeeding, think you may be pregnant or plan to have a baby. Your doctor will prescribe only if the benefits outweigh the risks.

    No, Human Papillomavirus Bivalent Vaccine Recombinant may not be effective against all types of human papillomavirus (HPV). Human Papillomavirus Bivalent Vaccine Recombinant protects against HPV types 16 and 18.

    Females aged nine to twenty-five years can get vaccinated with Human Papillomavirus Bivalent Vaccine Recombinant to prevent cancers caused by human papillomavirus (HPV) types 16 and 18.

    Human Papillomavirus Bivalent Vaccine Recombinant is not recommended to use in children less than nine years of age. Therefore, please consult your doctor if you have any concerns.

    Store Human Papillomavirus Bivalent Vaccine Recombinant in a refrigerator at a temperature of 2ºC to 8ºC. Do not freeze. Store in original package to protect from light. Keep out of reach of children.

    Available Medicines for

    Human Papillomavirus Bivalent Vaccine Recombinant

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