Hyoscyamine Sulphate
About Hyoscyamine Sulphate
Hyoscyamine Sulphate belongs to the group of anticholinergics and antispasmodics. Hyoscyamine Sulphate is used as adjuvant therapy in various abdominal disorders, including irritable bowel syndrome, inflammatory bowel disease and peptic ulcer disease. Hyoscyamine Sulphate is also used to treat muscular spasms in the kidney, bladder and stomach diseases, such as cystitis (UTI), diverticulitis, pancreatitis and gastric colic (spasmodic pain). In addition, Hyoscyamine Sulphate may be used to relieve tremors in patients who have Parkinson's disease. Hyoscyamine Sulphate also finds application as a desiccating (drying) agent in disorders of abnormal secretion such as excessive sweating, salivation and even diarrhoea. IBS is an intestinal and gastric disorder causing spasmodic pain in the abdomen. Peptic ulcer disease is a disorder characterised by rupturing of the inner lining of the gut caused by the action of excess stomach acid. Inflammation of the pancreas and urinary bladder is referred to as pancreatitis and cystitis, respectively.
Hyoscyamine Sulphate contains Hyoscyamine Sulphate, which is an anticholinergic. By blocking the activity of acetylcholine, Hyoscyamine Sulphate helps control disease caused by various secretions of the body such as sweat, saliva, urine, tears and faeces.. In addition, Hyoscyamine Sulphate also works as an antimuscarinic agent, relieving painful cramps produced in organs during disorder and disease.
Hyoscyamine Sulphate is a prescription-only medication. It will be administered by a healthcare professional; do not self-administer. You may experience pain, itching, swelling or redness around the site of injection, dry mouth, skin dryness, constipation, dizziness, fatigue and decreased urine output. Most of these side effects do not require medical attention and resolve gradually over time. However, you should talk to your doctor if these side effects persist.
You should inform the doctor if you are allergic to Hyoscyamine Sulphate or any of its components. Keep your doctor informed if you suffer from an enlarged prostate, bladder obstruction, intestinal obstruction, severe inflammatory bowel disease, toxic megacolon, myasthenia gravis or glaucoma. You should use Hyoscyamine Sulphate with caution in case of thyroid disease, kidney disease, heart problems, GERD or hypertension. Keep your doctor informed if you are on antacids, antidepressants, bisphosphonates, heart medicine or antihistamines. Discuss your entire surgical history with the doctor and any intestinal operations that you may have done in the past. Consult your doctor if you plan to get pregnant before taking Hyoscyamine Sulphate during pregnancy or if you are breastfeeding. Consult your doctor before taking alcohol with Hyoscyamine Sulphate as there may be an interaction. Avoid driving or operating heavy machinery while taking Hyoscyamine Sulphate as Hyoscyamine Sulphate may cause drowsiness or dizziness.
Uses of Hyoscyamine Sulphate
Medicinal Benefits
Hyoscyamine Sulphate is an anticholinergic/antimuscarinic drug used to control visceral spasms. It contains Hyoscyamine Sulphate. It is used primarily in the treatment of IBS and to treat peptic ulcers. Acetylcholine is a substance that controls and modulates the various secretions of the body, including sweat, saliva, urine, tears and faeces. By blocking the activity of acetylcholine (anticholinergic), Hyoscyamine Sulphate helps curb and treat disease states produced by an excess of these secretions. In addition, Hyoscyamine Sulphate also works as an antimuscarinic agent, relieving painful cramps and contractions produced in organs during disorder and disease.
Directions for Use
Storage
Side Effects of Hyoscyamine Sulphate
- Dry mouth
- Constipation
- Headache
- Blurred vision
- Difficulty sleeping
- Drowsiness
- Difficulty urinating
- Dizziness
- Pain, Itching, Swelling or Redness around the site of injection
Drug Warnings
Hyoscyamine Sulphate should not be used in case of any known allergy to either of the components. Keep your doctor informed if you suffer from an enlarged prostate, bladder obstruction, intestinal obstruction, severe inflammatory bowel disease, toxic megacolon, myasthenia gravis or glaucoma. Hyoscyamine Sulphate should be used with caution in case of thyroid disease, kidney disease, heart problems, GERD or hypertension. Keep your doctor informed if you are on any antacids. Discuss your entire surgical history with the doctor and any intestinal operations such as colostomy or ileostomy (relating to the colon and ileum, parts of the intestine) that may have been done in the past. Consult your doctor before using the Hyoscyamine Sulphate during pregnancy, breastfeeding, or even if you are trying to get pregnant. Keep your doctor informed if you are on any antacids, corticosteroids, anti-anxiety drugs, bisphosphonates, antifungal medicines, other anticholinergics, antidepressants, heart medication, muscle relaxants and or antihistamines. Hyoscyamine Sulphate may interact with alcohol, and please consult your doctor before use. Hyoscyamine Sulphate may cause dizziness and is not recommended to take while driving or operating heavy machinery.
Drug Interactions
Drug-Drug Interactions: Hyoscyamine Sulphate may interact with certain electrolytes (e.g. potassium chloride), certain medicines used to treat a kidney stone condition (e.g. potassium citrate), and medicines used to treat certain types of seizures (e.g. topiramate, zonisamide).
Drug-Food Interactions: Hyoscyamine Sulphate can interact with alcohol.
Drug-Disease Interactions: Hyoscyamine Sulphate may interact with diseases conditions, including a known hypersensitivity disorder, autonomic neuropathy (dysfunction of the nerves), GI obstruction, glaucoma, obstructive uropathy (a condition in which the flow of urine is blocked), reactive airway diseases, myasthenia gravis (abnormal weakness of certain muscles), and infectious diarrhoea.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAlcohol may increase the risk of drowsiness and dizziness. Hence, avoid consuming alcohol while taking Hyoscyamine Sulphate.
Pregnancy
cautionNot enough studies have been conducted to ascertain the effects of Hyoscyamine Sulphate on pregnancy. Hyoscyamine Sulphate should be used in pregnancy only if clearly needed. Hence, inform your doctor before receiving this medicine if you are pregnant.
Breast Feeding
cautionHyoscyamine Sulphate is excreted in breast milk and may affect your infant. Hence, inform your doctor before receiving this medicine if you are breastfeeding.
Driving
cautionHyoscyamine Sulphate may cause dizziness or loss of alertness, which may affect your ability to drive. Hence, drive only if you are alert after taking this medicine.
Liver
safe if prescribedHyoscyamine Sulphate is probably safe to be used in liver patients. Please consult your doctor in case of any concerns.
Kidney
safe if prescribedHyoscyamine Sulphate is excreted by the kidneys, and the risk of toxic reactions may be higher in patients with impaired kidney function. Elderly patients are more likely to have impaired renal function. Hence, the dose of this medicine is titrated by your doctor. Your doctor may suggest renal function tests while on treatment with Hyoscyamine Sulphate.
Children
cautionHyoscyamine Sulphate is not recommended for use in children less than two years of age. Your doctor may prescribe this medicine for children over two years of age, depending on the body weight and condition of the child. Please consult your physician if you have any concerns.
Habit Forming
Diet & Lifestyle Advise
- Cut back on fried foods and animal fats. Eat lean meats, healthy fats, fruits, vegetables and whole-grain foods. Change to a low FODMAP diet. This means avoiding (lactose (milk, ice cream, cheese, yoghurt), fruits like mangoes, apples and plums; legumes; corn syrup, sweeteners, wheat-based bread, cashews and pistachios)
- Avoid taking Hyoscyamine Sulphate with alcohol as there may be an interaction.
- Stay hydrated by drinking plenty of water, as dehydration is often seen after Hyoscyamine Sulphate.
- Hypnotherapy and meditation have also proven very effective in relieving symptoms of IBS and other psychosomatic gastric disorders. Check out such holistic treatments for the same.
- Yoga has also proven very effective in controlling many abdominal diseases and promoting good health and digestion. Try to do yoga at least thrice a week.
Special Advise
- Take Hyoscyamine Sulphate exactly as prescribed.
- If you miss a dose of Hyoscyamine Sulphate, take it as soon as possible. However, revert to the original schedule if it is too close to the next dose. Do not ever take a double dose.
- Please inform your doctor immediately if you accidentally take an extra dose of Hyoscyamine Sulphate. Common overdose symptoms can include anxiety, hives, shortness of breath, drowsiness, blurred vision, difficulty swallowing, and feeling hyper, agitated or nervous.
- Do not discontinue taking Hyoscyamine Sulphate abruptly or without the physician's advice.
- Please know that your doctor may order blood tests to check your tolerance and need a Hyoscyamine Sulphate.
- Older adults over 65 are not advised to take Hyoscyamine Sulphate unless warranted.
Patients Concern
Disease/Condition Glossary
Irritable Bowel Syndrome: IBS is an intestinal and gastric disorder causing spasmodic pain in the abdomen, flatulence, diarrhoea and constipation. It may be caused by an underlying disease or a food allergy. IBS also has psychological causes and can be precipitated by stress.
Peptic Ulcer Disease: An ulcer is a sore on the inner lining of an organ. Peptic ulcers are sore craters formed in the inner lining of the stomach or intestine due to the action of excessive hydrochloric acid. They are characterised by dyspepsia, gas, loss of appetite, heartburn, upper abdominal pain and fatigue.
Pancreatitis: Swelling of the pancreas is referred to as pancreatitis. It is commonly seen in alcoholics. It may be of sudden onset, or it may develop as a chronic condition. Nausea, vomiting and writhing abdominal pain are common symptoms of the disease.
Diverticulitis: Diverticula are outpouchings formed in the inner lining or mucosa of the intestine. Diverticulitis occurs when these pouches swell up and show signs of pain, inflammation, tenderness and soreness. Common symptoms are cramps, bloating, diarrhoea, flatulence and indigestion.
Cystitis: Inflammation of the urinary bladder is referred to as cystitis. It occurs because of urinary tract infections (UTIs). Common symptoms include burning or stinging sensation while urinating, loss of appetite, fatigue, lower back pain, frequent and cloudy, smelly urine, a sense of incomplete emptying of the bladder and fever.
FAQs
Hyoscyamine Sulphate belongs to the group of anticholinergics and antispasmodics. Hyoscyamine Sulphate is used as adjuvant therapy in various abdominal disorders, including irritable bowel syndrome, inflammatory bowel disease and peptic ulcer disease. Hyoscyamine Sulphate is also used to treat muscular spasms in the kidney, bladder and stomach diseases, such as cystitis (UTI), diverticulitis, pancreatitis and gastric colic (spasmodic pain).
Hyoscyamine Sulphate works by reducing abnormal secretions in the body and muscular contractions.
While Hyoscyamine Sulphate is very effective in relieving cramps, it is not routinely indicated for treating uterine cramps. Please consult your doctor in case of any concerns.
Hyoscyamine Sulphate is used as adjuvant therapy in IBD. Inform your doctor before taking Hyoscyamine Sulphate if you are using any other medication for IBD.
Hyoscyamine Sulphate is used in the treatment of underlying diseases that produce symptoms such as gas and flatulence. However, the reasons for gas can be varied. It is best to consult a doctor before use.
Hyoscyamine Sulphate is not known to affect fertility. Not enough studies exist on the same. Please consult your doctor in case of any concerns.
No, Hyoscyamine Sulphate is not an over-the-counter medication, it is a prescription medication which should not be used unless it is prescribed by the doctor.
Hyoscyamine Sulphate is neither steroid nor narcotic or sulfa drug. It belongs to a group of medications called anticholinergics and antispasmodics used to treat muscular spasms.
Yes, Hyoscyamine Sulphate is a muscle relaxant. It relaxes smooth muscles in the stomach, intestine and urinary tract to relieve cramps and spasms.
Consult the doctor before taking Hyoscyamine Sulphate with other medications to prevent any interactions. Let the doctor know if you are taking anticholinergics, antihistamines, antidepressants, opioid analgesics or antifungal medications.
Hyoscyamine Sulphate may stop diarrhoea if it is caused by muscle spasms or cramps in the intestines and helps to relieve the spasms and potentially reduce the frequency of diarrhoea. Hyoscyamine Sulphate is not known to cause diarrhoea, however individual reactions to the medication may vary. If you experience diarrhoea you can manage it by drinking plenty of water, taking probiotics and avoiding spicy, high-fibre food.
The side effects of Hyoscyamine Sulphate include injection site reactions, fatigue, constipation, dizziness, dry mouth, skin dryness and decreased urine output. Consult the doctor if any of these side effects persist or worsen.
Yes, Hyoscyamine Sulphate may cause constipation as a side effect. If you experience constipation you can manage it by drinking plenty of water, eating fibre-rich food and exercising regularly.
Hyoscyamine Sulphate may cause dizziness. Avoid driving or operating machinery if you experience dizziness.
Hyoscyamine Sulphate should be used during pregnancy only if prescribed by the doctor. Please consult the doctor if you have any concerns.
No drug-food interactions were found. However, limit alcohol intake as it may cause drowsiness and dizziness.
If you experience any side effects, you can manage it with lifestyle changes such as staying hydrated, increasing fibre intake, using a humidifier and exercising regularly.
Hyoscyamine Sulphate may interact with anticholinergics, antihistamines, antidepressants, opioid analgesics, antifungal medications (ketoconazole), antipsychotics (haloperidol) and certain medications used to treat a kidney stone condition (potassium citrate). Consult the doctor before taking these medications with Hyoscyamine Sulphate.
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