Imeglimin Hydrochloride
About Imeglimin Hydrochloride
Imeglimin Hydrochloride is an antidiabetic medicine used for the treatment of Type II Diabetes. Type II Diabetes Mellitus is a serious condition wherein the body doesn’t use insulin effectively, which causes unusual blood glucose levels. Type II diabetes patients either do not create enough insulin, or the insulin they do make does not accomplish its purpose in the body (insulin resistance). This condition mostly occurs in middle-aged or older patients.
Imeglimin Hydrochloride contains Imeglimin, which belongs to the amino triazines class of antidiabetic medicine. It works in two ways: 1) increased glucose-stimulated insulin secretion (GSIS) and cell mass preservation; 2) improved insulin action, including the potential for reduction of hepatic glucose output and improvement in insulin signalling in both the liver and skeletal muscle. Diet management and exercise, along with treatment of Imeglimin Hydrochloride are used to control blood sugar levels.
Imeglimin Hydrochloride may cause certain side effects such as vomiting, nausea, abdominal pain, headache and allergic reactions. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Imeglimin Hydrochloride should be taken as prescribed by your doctor. It can be taken with or without food. The dose of the medicine will be decided by the doctor based on your disease condition.
Imeglimin Hydrochloride should be avoided if you are allergic to any of the medicines or the components in it. Inform your doctor about your medical history and the medicines you are taking, including herbs and supplements, before starting the treatment with Imeglimin Hydrochloride. This can help prevent unwanted effects. Imeglimin Hydrochloride is not recommended for use in patients with severe liver or kidney disease. It is unknown whether Imeglimin Hydrochloride can be given to pregnant women or breastfeeding mothers. Hence, inform your doctor if you are pregnant or breastfeeding before taking Imeglimin Hydrochloride. It is not recommended for use in children below 18 years of age.
Uses of Imeglimin Hydrochloride
• Controls blood sugar levels: Imeglimin Hydrochloride is indicated for patients with type 2 diabetes to help improve glycaemic control.
• Used as part of diabetes management: Imeglimin Hydrochloride may be given alone or in combination with other antidiabetic medications and lifestyle measures.
Medicinal Benefits
Imeglimin Hydrochloride contains Imeglimin, which belongs to the aminotriazines class of antidiabetic medicine. It works in two ways: 1) increased glucose-stimulated insulin secretion (GSIS) and cell mass preservation; 2) improved insulin action, including the potential for reduction of hepatic glucose output and improvement in insulin signalling in both the liver and skeletal muscle. Diet management and exercise, along with treatment of Imeglimin Hydrochloride are used to control blood sugar levels.
Directions for Use
Storage
Side Effects of Imeglimin Hydrochloride
- Headache
- Nausea
- Stomach upset
- Vomiting
- Abdominal pain
Drug Warnings
Imeglimin Hydrochloride should be avoided if you are allergic to any of the medicines or the components in it. Before starting the treatment, inform your doctor about your medical history and the medications you take, including herbs and supplements. This can help prevent unwanted effects. Imeglimin Hydrochloride is not recommended for use in patients with severe liver or kidney disease. It is unknown whether Imeglimin Hydrochloride can be given to pregnant women or breastfeeding mothers. Hence, inform your doctor if you are pregnant or breastfeeding. It is not recommended for use in children below 18 years of age.
Drug Interactions
Drug-Drug Interactions: Imeglimin Hydrochloride interacts with an anti-depressant (bupropion), drugs used to treat glaucoma, antibiotics (cephalexin, ciprofloxacin), anti-acidity drugs (cimetidine), heart condition drugs (digoxin), anti-epileptic drugs (topiramate, lamotrigine), heart-related chest medicine (ranolazine).
Drug-Food Interactions: Intake of excessive alcoholic beverages may increase the chance of a life-threatening condition known as Lactic Acidosis. So, avoid intake of alcoholic beverages with Imeglimin Hydrochloride.
Drug-Disease Interactions: Inform your doctor if you have any kidney or liver disease or heart problems.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
consult your doctorIt is unknown whether Imeglimin Hydrochloride will interact with alcohol. Please consult a doctor before consuming alcohol while on treatment with Imeglimin Hydrochloride.
Pregnancy
cautionImeglimin Hydrochloride is not recommended in pregnancy as it may cross the placental barrier and harm your foetus. If you are pregnant or planning pregnancy, inform your doctor before taking Imeglimin Hydrochloride.
Breast Feeding
cautionImeglimin Hydrochloride passes into the breastmilk in traces. Hence, if you are breastfeeding, inform your doctor before taking Imeglimin Hydrochloride. Your doctor may prescribe this medicine if the benefits outweigh the risks.
Driving
safeImeglimin Hydrochloride usually does not affect your ability to drive or operate machinery.
Liver
cautionUse Imeglimin Hydrochloride with caution, especially if you have a history of liver disease. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Kidney
cautionUse Imeglimin Hydrochloride with caution, especially if you have a history of kidney disease. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Children
unsafeImeglimin Hydrochloride is not recommended for children below 18 years as the safety and effectiveness were not established.
Habit Forming
Diet & Lifestyle Advise
- Try doing 30 minutes of moderate-intensity physical activity or one hour and 15 minutes of high-intensity exercise weekly.
- Include your diet with whole grain foods, fruits and veggies and other fiber-enriched foods.
- Add omega-3 fatty acid-containing oils for daily cooking.
- Avoid too much stress, as it may elevate your blood sugar level. To control stress-related blood sugar changes, you can adopt stress management techniques like mindfulness, meditation, or yoga.
- Loss of weight gradually to achieve a healthy body mass index (18.5 to 24.9).
- Keep your blood pressure as normal (140/90) as possible, as it reduces the risk of cardiovascular diseases in diabetes patients.
- Avoid smoking and alcohol consumption while on treatment with Imeglimin Hydrochloride.
- Take short, frequent meals, and avoid prolonged fasting when taking Imeglimin Hydrochloride.
Special Advise
- Imeglimin Hydrochloride may sometimes cause hypoglycemia (low blood sugar levels) as a side effect. Try to carry candies or sugar biscuits in your pocket every time you feel symptoms such as sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination, etc.
- Inform your physician about all your underlying conditions, like kidney disease or liver disease, prior heart attack, alcohol intake, etc., before the doctor prescribes you Imeglimin Hydrochloride.
- Avoid drinking alcohol while on Imeglimin Hydrochloride as it increases the risk of hypoglycemia (decrease in blood sugar, which might be fatal in some cases) and lactic acidosis (when the lactic acid increases in the body, which impacts the functioning of various organs in the body).
- Lifestyle modifications are the most important step in controlling blood sugar levels.
- Your doctor may advise frequent blood tests to check your blood sugar levels.
Patients Concern
Disease/Condition Glossary
Type II Diabetes Mellitus: It is a chronic and lifelong condition wherein the body doesn’t use insulin effectively, which causes unusual blood glucose levels. Therefore, people affected with type 2 diabetes either do not produce enough insulin or there is resistance to the action of insulin. Individuals middle-aged or older are most likely to suffer from type 2 diabetes, which is also known as adult-onset diabetes. Symptoms of type 2 diabetes include increased thirst, frequent urination at night, slow wound healing, increased hunger, fatigue, weight gain, and blurred vision. The complication of type 2 diabetes also includes neuropathy (nerve problems), nephropathy (kidney problems), retinopathy (damaged retina of eyes or blindness), loss of limbs, sexual dysfunction, and increased chance of heart attack or stroke.
FAQs
Imeglimin Hydrochloride is used for the treatment of Type II Diabetes, a condition in which the body does not use insulin effectively, leading to abnormal blood glucose levels.
The side effects of Imeglimin Hydrochloride include abdominal pain, vomiting, nausea, and headache. Most of these side effects resolve gradually on their own over time. However, consult the doctor if any of these symptoms persist or worsen.
Imeglimin Hydrochloride contains imeglimin that works by increasing glucose-stimulated insulin secretion (GSIS) and preserving pancreatic cell function. Additionally, it improves insulin action by reducing hepatic glucose production and enhancing insulin sensitivity in both the liver and skeletal muscle, helping to regulate blood glucose levels effectively.
Imeglimin Hydrochloride is an antidiabetic medication used to treat Type II Diabetes. It enhances insulin secretion, protects beta-cell function, and enhances insulin effectiveness in the liver and muscles. This helps reduce glucose production and increase insulin sensitivity. Along with diet and exercise, it aids in blood sugar control.
The dosage of Imeglimin Hydrochloride depends on various factors such as the patient's medical condition, age, weight, and response to treatment. Please consult a doctor for the appropriate dose.
Imeglimin Hydrochloride can be taken with caution if you have a history of kidney disease. Please consult the doctor, as they may adjust the dose of this medication or prescribe a suitable alternative based on your medical condition.
Some individuals may experience dizziness, which may impact daily activities. To ensure safety, avoid driving or operating heavy machinery until you understand how it affects you. Please consult the doctor if dizziness is severe or persistent to rule out any underlying issues.
To relieve constipation while taking Imeglimin Hydrochloride, increase fibre intake through fruits, vegetables, and whole grains. Stay hydrated by drinking plenty of water and fluids. Avoid processed foods and consider probiotics for better absorption. Please consult your doctor for personalized advice if constipation persists.
No, Imeglimin Hydrochloride is not used to treat Type 1 Diabetes. It is specifically designed to manage and treat Type 2 Diabetes, as it enhances insulin secretion and improves insulin action. Type 1 Diabetes requires insulin therapy, so please consult your doctor for appropriate treatment.
Avoid excessive alcohol consumption while taking Imeglimin Hydrochloride, as it may increase the risk of lactic acidosis, a serious condition. Additionally, limit processed foods, sugary foods, and high-fat meals that can affect blood sugar control.
Imeglimin Hydrochloride is generally considered safe when taken as directed by your doctor. However, to ensure your safety, it's essential to consider your individual health conditions, especially if you have pre-existing kidney or liver diseases or a history of lactic acidosis. Before starting Imeglimin Hydrochloride, consult your doctor to discuss potential risks and benefits. Additionally, regular monitoring of your condition and check-ups with your doctor is crucial to minimize potential side effects and ensure safe usage.
Do not stop taking Imeglimin Hydrochloride without consulting the doctor. Stopping the medication abruptly may lead to uncontrolled blood sugar levels, and your diabetes symptoms may worsen. Please consult the doctor if you need to discontinue they will advise you on a safe approach.
Yes, people with diabetes can consume proteins as part of a balanced diet. Protein is an essential nutrient that helps regulate blood sugar levels and supports muscle health. However, it's best to choose lean proteins like fish, poultry, eggs, tofu, and legumes while limiting processed or high-fat meats.
Artificial sweeteners can be a helpful alternative for people with diabetes, as they provide sweetness without raising blood sugar levels. However, it’s essential to consume them in moderation and choose options that are suitable for people with diabetes. Always consult your doctor for personalised advice.
Yes, diabetes can cause kidney failure if blood sugar levels remain uncontrolled over time. High blood sugar damages the kidney's filtering units (nephrons), leading to diabetic nephropathy, a major cause of chronic kidney disease (CKD). Maintaining healthy blood sugar levels, a well-balanced diet, and regular medical check-ups can help prevent kidney damage.
Diabetes cannot be cured completely however it can be managed effectively. Type 1 Diabetes requires lifelong insulin therapy, while Type 2 Diabetes can sometimes be controlled through diet, exercise, medication, and weight management. In some cases, remission can occur, but ongoing lifestyle management is crucial. Always consult your doctor for the best treatment plan.
