Losartan+amlodipine
About Losartan+amlodipine
Losartan+amlodipine is used to treat high blood pressure (hypertension). Hypertension is a medical condition in which blood pressure is elevated persistently in the arteries.
Losartan+amlodipine contains Losartan and Amlodipine. Losartan lowers blood pressure and increases blood flow by preventing the narrowing of blood vessels. Amlodipine dilates (widens) blood vessels and increases blood flow.
In some cases, Losartan+amlodipine can cause side effects like sleepiness, taste changes, headache, dizziness, tiredness, and upset stomach. Most of these side effects do not require medical attention and resolve over time. However, if these side effects persist longer, please consult your doctor.
If you are known to be allergic to Losartan+amlodipine or any other medicines, please inform your doctor. Before taking Losartan+amlodipine, let your doctor know if you have any kidney or liver problems or severe dehydration.
Uses of Losartan+amlodipine
Medicinal Benefits
- Losartan+amlodipine is a combination anti-hypertensive medicine used to treat high blood pressure (hypertension) and related heart conditions.
- It contains Losartan and Amlodipine, which work together to improve blood flow and reduce strain on the heart.
- It helps reduce elevated blood pressure, decreasing the risk of stroke, heart attack, and kidney problems.
- Losartan (an angiotensin II receptor antagonist) prevents blood vessel narrowing, promoting smooth blood flow.
- Amlodipine (a calcium channel blocker) relaxes blood vessel walls, improving circulation and lowering pressure.
- It reduces the heart’s workload, helping it pump blood more efficiently.
- It improves oxygen supply to the heart muscles, helping prevent or reduce chest discomfort caused by coronary artery disease.
- The dual mechanism of action provides better blood pressure control and improved cardiovascular outcomes compared to single-drug therapy.
Directions for Use
- Losartan+amlodipine can be taken with or without food as advised by your doctor.
- Follow your doctor's instructions on the dosage and timing of this medication.
- Swallow Losartan+amlodipine as a whole with a glass of water.
- Do not crush, break, or chew it.
Storage
Side Effects of Losartan+amlodipine
- Sleepiness
- Taste changes
- Ankle swelling
- Headache
- Flushing
- Dizziness
- Tiredness
- Palpitations
- Upset stomach
- Hyperkalaemia
Drug Warnings
- If you are known to be allergic to Losartan+amlodipine or have any kidney or liver problems or severe dehydration, please inform your doctor beforehand.
- Pregnant or breastfeeding women should also consult their doctor before taking this medicine.
- Complete the course as suggested by the doctor, even if you feel better, to avoid disease recurrence.
- Avoid consumption of alcohol with Losartan+amlodipine as it may increase the risk of low blood pressure.
- Avoid potassium supplements with Losartan+amlodipine as it may lead to high potassium levels in the blood.
- Let your doctor know if you are taking any other medicines, including supplements or herbal products.
Drug Interactions
Drug-Drug Interaction: Losartan+amlodipine may interact with other blood pressure treating medicines (Lisinopril, Ramipril, benazepril), pain killers (aspirin, ibuprofen, naproxen, celecoxib, diclofenac, indomethacin, meloxicam, hydrocodone), heart-related medicines (metoprolol, nitroglycerin), high cholesterol treating drugs (simvastatin), fluid retention drugs (hydrochlorothiazide), and drugs treating impotence (sildenafil).
Drug-Food Interaction: Minimise high potassium foods intake and avoid over-the-counter potassium supplements, grapefruit, or juice.
Drug-Disease Interaction: People with low blood pressure, heart, kidney or liver problems or severe dehydration, hyperkalaemia (high potassium levels in the blood), and diabetes should consult a doctor before taking Losartan+amlodipine.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeIt is unsafe to consume alcohol, since alcohol consumption with Losartan+amlodipine may increase the risk of low blood pressure and cause adverse effects such as dizziness, fainting, light-headedness, or headache.
Pregnancy
cautionPlease consult your doctor before taking Losartan+amlodipine if you plan to become pregnant or are already pregnant. Your doctor will weigh the potential risks and benefits before prescribing Losartan+amlodipine.
Breast Feeding
cautionThere is no evidence on how Losartan+amlodipine affects breastfeeding. Please consult your doctor before taking Losartan+amlodipine if you are breastfeeding.
Driving
cautionLosartan+amlodipine may cause side effects like dizziness, headaches, nausea or tiredness, which can affect your ability to concentrate and drive. Hence, it is recommended not to drive or operate machinery until you are mentally alert.
Liver
cautionLet your doctor know if you have any history of liver diseases before taking Losartan+amlodipine. The dosage will be initiated in lower doses and will be further increased in patients with liver diseases.
Kidney
cautionLosartan+amlodipine consists of Losartan, which may affect kidney function. Hence, it is advised to seek a doctor's advice before starting Losartan+amlodipine if you have kidney problems.
Children
cautionIt is not recommended for children below six years. However, for children above six years, give Losartan+amlodipine in doses as prescribed by a doctor.
Habit Forming
Diet & Lifestyle Advise
- Reduce sodium intake in your diet to maintain your blood pressure.
- Eat natural and healthy foods by cutting down on high-sodium processed foods.
- Lose those extra pounds, since being obese can be a risk factor for hypertension.
- Exercise regularly to maintain good heart health.
- Avoid smoking and alcohol intake.
- Chronic stress may also cause high blood pressure. Therefore, avoid stress triggers and make time for yourself to relax and do activities that you enjoy.
Special Advise
Keep a check on your daily blood pressure, and if you notice any fluctuations, please consult a doctor. Low salt/sodium diet and regular exercise are recommended along with Losartan+amlodipine for effective results.
Patients Concern
Disease/Condition Glossary
High blood pressure is the measurement of the force that our heart uses to pump blood to all parts of the body. Hypertension is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure.
FAQs
Losartan+amlodipine is used to treat high blood pressure (hypertension).
Losartan+amlodipine consists of Losartan and Amlodipine. Losartan lowers blood pressure and increases blood flow by preventing the narrowing of blood vessels. Amlodipine dilates (widens) blood vessels and increases blood flow. Altogether, Losartan+amlodipine helps to lower high blood pressure, chest pain (angina) and other conditions caused by coronary artery disease.
Losartan+amlodipine can cause high levels of potassium in the blood, leading to hyperkalaemia. Hence, it is not recommended to use potassium supplements along with Losartan+amlodipine. However, consult your doctor if you are already taking other medicines before starting Losartan+amlodipine.
Do not stop using Losartan+amlodipine even if you feel better. It should be strictly used as advised by your doctor to avoid the recurrence of symptoms and worsening of the disease.
The duration you take Losartan+amlodipine depends on your health needs and blood pressure control. Typically, high blood pressure requires ongoing treatment. Your doctor will closely monitor your progress and decide how long you should continue taking the medication. It's essential not to stop taking Losartan+amlodipine without consulting your doctor first, as they will adjust your treatment plan accordingly.
Follow a balanced diet in moderation, accentuating natural and healthy foods, fresh fruits and vegetables, whole grains, low-fat or fat-free dairy products, and lean protein sources like poultry, fish, legumes, nuts and seeds. Legumes like beans and lentils are also great additions. Remember to limit your sodium intake to help manage your blood pressure. Aim for variety and inclusivity in your diet to ensure you're getting all the essential nutrients. By following this diet, you'll be well on your way to supporting your overall health and well-being! If you have specific dietary needs or restrictions, always consult with a healthcare professional or registered dietitian for personalized guidance.
Yes, you can take Losartan+amlodipine on an empty stomach. However, if you experience stomach upset or discomfort, taking it with food may help alleviate these symptoms. Consult your doctor or pharmacist for personalized advice.
When managing hypertension with medication, it's crucial to monitor your blood pressure regularly and maintain open communication with your healthcare provider. This includes sharing any pre-existing kidney issues or concerns about pregnancy or breastfeeding. Additionally, be mindful of dehydration and potential allergic reactions, which can impact your overall well-being. By taking these precautions and being proactive about your health, you can effectively manage your hypertension and reduce the risk of related complications.
Yes, you may feel dizzy after taking Losartan+amlodipine. This is one of the most common side effects of Losartan+amlodipine because it lowers blood pressure and increases blood flow, which makes you feel dizzy, especially during quick actions (standing, walking, lying). To manage it, stay hydrated and take slow actions while sitting or lying. If dizziness is increasing, consult your doctor; he will help you manage your condition.
Please consult your doctor before taking Losartan+amlodipine if you plan to become pregnant or are already pregnant. Your doctor will weigh the potential risks and benefits before prescribing Losartan+amlodipine.
Adopting a healthy lifestyle is crucial when managing hypertension. Focus on consuming a balanced diet rich in whole foods, fruits, and vegetables and limiting your sodium intake. Regular exercise can also help maintain good heart health. Additionally, avoid smoking and alcohol consumption and find ways to manage stress, such as relaxation techniques or engaging in enjoyable activities. By making these lifestyle changes, you can significantly improve your overall health and well-being.
The most common side effects of the Losartan+amlodipine are ankle swelling, dizziness, flushing, headache, hyperkalaemia, palpitations, sleepiness, taste changes, tiredness, and upset stomach, which can have a lasting impact and vanish as time goes on. Inform your doctor if you feel more uncomfortable with the symptoms.
Losartan+amlodipine is not recommended for children under 6 years old. For children over 6, follow a doctor's instructions for proper dosing and usage. If your child has hypertension, consult with your doctor to discuss the best course of treatment, including medication and lifestyle changes. Your doctor will help you develop a plan to manage your child's condition and promote healthy habits.
Keep Losartan+amlodipine in its original container, stored at room temperature away from moisture and light. Keep it out of the reach of children and pets. When disposing of medication, don't flush it down the toilet. Instead, take unused or expired medicines to a pharmacy or drug take-back location. Ask your pharmacist or healthcare provider for guidance if you're unsure about proper disposal. Following these simple steps will help ensure safety and responsibility when storing and disposing of medication.
