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About METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID

METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID belongs to the class of 'Vitamins', primarily used to treat nutritional deficiencies. It is used to treat and prevent vitamin B6 deficiency, folate deficiency and vitamin B12 deficiency. METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID effectively treats various conditions caused due to lack of vitamins, such as anaemia (lack of red blood cells), peripheral neuropathy (nerve disorder), seizures (fits), hyperoxaluria (excess oxalate levels in urine), homocystinuria (accumulation of an amino acid called homocysteine in urine and blood), cyanide poisoning and hyperhomocysteinemia (high levels of homocysteine in the blood).

METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID contains Folic acid, Pyridoxine Hydrochloride, and Methylcobalamin. Folic acid is the synthetic form of folate. Folate is a water-soluble vitamin naturally found in food sources. It helps in the formation of red blood cells and prevents DNA changes that may lead to cancer. Pyridoxine Hydrochloride (also known as vitamin B6) is a water-soluble vitamin involved in protein, fat, and carbohydrate metabolism and the formation of red blood cells and neurotransmitters. Mecobalamin (Methylcobalamine) is a coenzyme form of vitamin B12 that regulates body functions, such as cell multiplication, blood formation, and protein synthesis.

Your doctor will decide the dosage based on your medical condition. Sometimes, METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID may have common side effects like upset nausea, stomach upset, diarrhoea, drowsiness, flushing, and numbness/tingling. These side effects do not require medical attention and gradually resolve over time.  

Let your doctor know if you are using ant other medicines before starting METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID. If you are known to be allergic to METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID or its inactive components, please inform your doctor. Vitamins are absorbed readily through oral administration. Please tell your doctor if you have malabsorption syndrome (difficulty absorbing nutrition from food). The dosage form may be changed to intravenous administration of individual vitamins for better absorption of METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID. If you are a pregnant or breastfeeding mother, please consult your doctor before taking METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID.

Uses of METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID

Nutritional deficiencies, anaemia, folate deficiency, Vitamin B12 deficiency and Vitamin B6 deficiency. 

Medicinal Benefits

METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID is used to treat nutritional deficiencies and contains Folic acid, Pyridoxine Hydrochloride, and Methylcobalamin. Folic acid is the synthetic form of folate, a water-soluble Vitamin B that prevents and treats folate deficiency and hyperhomocysteinemia. When used with other medications, Folic acid is used to treat pernicious, aplastic, or normocytic anemia (lack of red blood cells). When taken by pregnant women, Folic acid prevents miscarriage and neural tube defects in infants. Pyridoxine Hydrochloride (vitamin B6) is a water-soluble vitamin that treats and prevents vitamin B6 deficiency, anemia, peripheral neuropathy, seizures (fits), and hereditary disorders like hyperoxaluria and homocystinuria. It is involved in protein, fat, and carbohydrate metabolism and the creation of red blood cells and neurotransmitters. It helps in cognitive development through neurotransmitter biosynthesis and maintains normal homocysteine levels (an amino acid in the blood). Methylcobalamin (Mecobalamin) is a coenzyme form of vitamin B12 and treats Vitamin B12 deficiency, cyanide poisoning, and hyperhomocysteinemia. It regulates body functions, such as cell multiplication, blood formation, and protein synthesis.

Directions for Use

Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID

  • Nausea

  • Stomach upset

  • Diarrhoea

  • Drowsiness

  • Flushing

  • Numbness/tingling 

In-Depth Precautions and Warning

Drug Warnings

Let your doctor know if you have any blood disorders like pernicious anaemia before starting METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID. Pyridoxine and folic acid in METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID are excreted into the breast milk. Pregnant or breastfeeding women should consult their doctor before taking METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID. Excessive alcohol consumption reduces the absorption and increases the elimination of folic acid. Alcohol can also worsen the side effects like drowsiness and stomach upset. Hence, please avoid alcohol while using METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID.

Drug Interactions

Drug-Drug Interaction: METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID may interact with anti-cancer drugs (altretamine, cisplatin, and arsenic trioxide), fits medicines (phenytoin, phenobarbital, primidone), antibiotic (chloramphenicol), medicines treating Parkinson's disease (levodopa), drugs used to treat tumours (Fluorouracil), antibiotics (trimethoprim), stomach related drugs (sulfasalazine), and cholesterol-lowering drugs (cholestyramine).

Drug-Food Interaction: Excessive alcohol consumption reduces the absorption and increases the elimination of folic acid. Alcohol can also worsen the side effects like drowsiness and stomach upset.

Drug-Disease Interaction: Use METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID with medical advice if you have malabsorption syndrome (difficulty absorbing nutrition from food) and allergic reactions to medicines.

Drug-Drug Interactions Checker List:

  • ALTRETAMINE
  • CISPLATIN
  • ARSENIC TRIOXIDE
  • PHENYTOIN
  • PHENOBARBITAL
  • PRIMIDONE
  • CHLORAMPHENICOL
  • LEVODOPA
  • FLUOROURACIL
  • TRIMETHOPRIM
  • SULFASALAZINE
  • CHOLESTYRAMINE
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Excessive alcohol consumption reduces absorption and increases the elimination of folic acid. Hence, please avoid alcohol while using METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID.

    • Safety Warning

      Pregnancy

      caution

      METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID should be used during pregnancy only when advised by your doctor. Let your doctor know if you are pregnant or planning to conceive before taking METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID.

    • Safety Warning

      Breast Feeding

      caution

      Pyridoxine and Folic acid in METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID are excreted into the breast milk. Please consult your doctor before taking METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID if you are a breastfeeding mother.

    • Safety Warning

      Driving

      safe

      METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID usually does not affect your driving ability and is safe to use.

    • Safety Warning

      Liver

      caution

      Let your doctor know if you have any history of liver diseases before taking METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID.

    • Safety Warning

      Kidney

      caution

      Let your doctor know if you have any history of kidney diseases before taking METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID.

    • Safety Warning

      Children

      consult your doctor

      The doctor will advise the dosage of METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID based on the child's age and weight.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Try Vitamin B complex food sources like milk, cheese, eggs, liver and kidney, chicken, red meat, tuna, mackerel, and salmon, shellfish, oysters, clams, dark green vegetables, such as spinach and kale, beets, avocados, potatoes, whole grains, cereals, kidney beans, black beans, and chickpea.

    • Try folate-rich food sources like broccoli, Brussels sprouts, leafy green vegetables, cabbage, kale, spring greens, spinach, peas, chickpeas, kidney beans, liver (avoid this during pregnancy), and breakfast cereals fortified with folic acid.

    • Sprinkle sunflower seeds over your food, vegetables and salads. 

    • Include fruits like citrus, banana and watermelon in your diet.

    • Avoid smoking and alcohol consumption.

    • Exercise regularly, and maintain a healthy lifestyle. Avoid excess fatty foods.

    Special Advise

    • Clinical monitoring of folic acid, vitamins B12 and B6 levels through blood examinations is recommended.

    • Let your doctor and the laboratory staff know if you are using METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID since Pyridoxine may interfere with laboratory tests like urine test for urobilinogen.

    Patients Concern

    Disease/Condition Glossary

    Vitamin B6 deficiency: When your body doesn't have adequate levels of a water-soluble vitamin called Pyridoxine or Vitamin B6, this disease is developed. Vitamin B6 deficiency symptoms include fatigue, skin rashes, cracked and sore lips, weak immune system, tiredness and low energy levels, fits, tingling in hands and feet.

    Vitamin B12 deficiency (cobalamin deficiency): When your body doesn't have adequate mineral levels called Vitamin B12, it leads to Vitamin B12 deficiency. Symptoms include fatigue, breathlessness, numbness, poor balance and memory trouble.

    Folate deficiency: Folate deficiency occurs when your body won't have enough folate in your diet. Symptoms include fatigue, grey hair, mouth sores, tongue swelling and growth problems. Folate deficiency leads to anaemia.

    Anaemia: It is a condition associated with a decrease in the red blood cells (RBCs) count or haemoglobin in the blood or a lowered ability to carry oxygen. Symptoms include fatigue, shortness of breath, light-headedness, dizziness and fast heartbeat.

    FAQs

    How does METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID work?

    METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID is a vitamin supplement and consists of Folic acid, Pyridoxine HCl (vitamin B6) and Methylcobalamin (vitamin B12). When you lack these vitamins in your body, which cannot be recovered even with the food sources, METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID helps in normalising these deficient levels. Collectively, METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID treats nutritional deficiencies.

    How can I manage Folic acid/folate deficiency?

    Folate deficiency occurs when your body lacks adequate folic acid/folate levels. You can overcome this deficiency by including food sources rich in folic acid like broccoli, brussels sprouts, leafy green vegetables, cabbage, kale, spring greens, spinach, peas, chickpeas, kidney beans, liver (avoid this during pregnancy) and breakfast cereals fortified with folic acid. If your folic acid levels are still low, your doctor may suggest its supplements.

    Does METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID cause any abnormal test results?

    Pyridoxine in METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID may interfere with laboratory tests like urine test for urobilinogen. Please make sure your doctor and the laboratory staff know that you take METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID before undergoing any blood and urine examinations.

    What happens if I miss a dose?

    If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.

    Available Medicines for

    METHYLCOBALAMIN+PYRIDOXINE HCL+FOLIC ACID