Naproxen Sodium+domperidone
About Naproxen Sodium+domperidone
Naproxen Sodium+domperidone is primarily used in the treatment of migraine headaches. Migraine is a type of headache, usually on one side, often with nausea and sensitivity to light and sound.
Naproxen Sodium+domperidone is a combination of two drugs: Naproxen Sodium and Domperidone. Naproxen Sodium blocks COX enzymes that produce chemicals causing pain and swelling. Domperidone stops nausea and vomiting by blocking signals in the brain that cause vomiting.
The most common side effects of Naproxen Sodium+domperidone are dry mouth, confusion, headache, ringing in the ears, changes in vision, tiredness, dizziness, drowsiness, and rashes. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.
If you are known to be allergic to any of the components in Naproxen Sodium+domperidone, please inform your doctor. Consult your doctor before taking Naproxen Sodium+domperidone if you are pregnant or breastfeeding. Naproxen Sodium+domperidone should be used in children under 12 only if prescribed by a paediatrician.
Uses of Naproxen Sodium+domperidone
Medicinal Benefits
- Naproxen Sodium+domperidone is a combination of Naproxen sodium and Domperidone used to treat migraine.
- Naproxen sodium is an anti-inflammatory (reduces inflammation) and analgesic (reduces pain) agent. It inhibits the synthesis of prostaglandins, which are inflammatory mediators, thereby reducing pain and inflammation.
- Domperidone acts by enhancing gastric peristalsis (movements) on an empty stomach. It also blocks the dopamine receptors at the chemoreceptor trigger zone (responsible for regulating nausea and vomiting).
- Naproxen Sodium+domperidone can also treat pain associated with rheumatoid arthritis, arthritis, gout, dysmenorrhea (menstrual pain), and muscle and bone disorders, such as back pain, sprains, and strains.
- Naproxen Sodium+domperidone also controls nausea and vomiting associated with migraine.
Directions for Use
- Naproxen Sodium+domperidone can be taken with meals, to avoid stomach upset, or as advised by your doctor.
- Follow your doctor’s instructions on the dosage and timing of this medication.
- Swallow the tablet as a whole with a glass of water.
- Do not crush, chew, or break it.
Storage
Side Effects of Naproxen Sodium+domperidone
- Dry mouth
- Headache
- Confusion
- Feeling sleepy or tired
- Feeling dizzy
- Ringing in the ears
- Changes in vision
- Rashes
Drug Warnings
- Before using this Naproxen Sodium+domperidone, inform your doctor if you have any known allergies to Naproxen Sodium, Domperidone, other NSAIDs, or other drugs.
- Inform the doctor if you have a history of heart rhythm problems or ulcers caused by non-steroidal anti-inflammatory drugs (NSAIDs).
- Call for medical help immediately if you experience chest pain, shortness of breath, blood in the stool or dark stools, heartburn, or any other abnormal signs.
- Patients over the age of 65, those with pre-existing cardiac diseases such as heart failure, myocardial infarction, ischemic heart disease, hypertension, or stroke, gastrointestinal bleeding (due to pain relievers), gastric ulcers, respiratory diseases such as asthma, liver diseases, kidney diseases, or bleeding disorders should only take Naproxen Sodium+domperidone if a doctor has prescribed it.
Drug Interactions
Drug-drug interactions: Naproxen Sodium+domperidone may interact with other NSAIDs (ibuprofen, aspirin), anticoagulants (warfarin), corticosteroids (prednisolone), diuretics (furosemide), antihypertensive medications (ramipril, amlodipine), antidepressants (citalopram), and medicines used to treat rheumatoid arthritis (methotrexate).
Drug-food interactions: Limit or quit the consumption of Alcoholic beverages.
Drug-disease interactions: Naproxen Sodium+domperidone may interact with disease conditions, including asthma, fluid retention (Congestive Heart Failure, Hypertension), GI toxicity (Gastrointestinal Haemorrhage, Gastrointestinal Perforation, Gastritis), rash, renal toxicities (Renal Dysfunction), and thrombosis (a condition in which a blood clot blocks a vein).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consuming alcohol while using Naproxen Sodium+domperidone.
Pregnancy
cautionNaproxen Sodium+domperidone should be used in pregnant women only if clinically needed. If you are pregnant, please consult your doctor before taking this medicine. Your doctor may prescribe Naproxen Sodium+domperidone if the benefits outweigh the risks.
Breast Feeding
consult your doctorNaproxen Sodium+domperidone is considered safe for use during breastfeeding. However, consult your doctor before taking this medicine if you are breastfeeding.
Driving
cautionNaproxen Sodium+domperidone may impact your ability to drive or operate machinery. Drive only if you are alert.
Liver
consult your doctorLimited information was available for the use of Naproxen Sodium+domperidone in patients suffering from liver impairment. Please consult your doctor if you have any concerns regarding using Naproxen Sodium+domperidone in patients with liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.
Kidney
consult your doctorLimited information was available regarding the use of Naproxen Sodium+domperidone in patients with kidney impairment. Please consult your doctor if you have any concerns regarding using Naproxen Sodium+domperidone in patients with kidney impairment.
Children
cautionNaproxen Sodium+domperidone should be used in children below 12 years of age only when prescribed by a doctor.
Habit Forming
Diet & Lifestyle Advise
- Drink plenty of fluids to avoid gastrointestinal problems.
- Avoid triggers that can increase your migraine headaches.
- Take enough rest.
- Acupuncture, massage and physical therapy may also be helpful.
- De-stress yourself by meditating, reading a book, taking a warm bubble bath, or listening to soothing music.
- Practising yoga may also help improve joint flexibility and manage pain.
- Get adequate sleep, as rest can help reduce inflammation and swelling.
- Taking meals at the same time every day and getting sufficient sleep may help prevent migraine attacks.
- You are recommended to avoid loud music, noisy places, extreme temperatures and bright light.
- Avoid consuming chocolates, cheese, processed food, smoking and alcohol.
Special Advise
- Your doctor may monitor your liver and kidney function if you take Naproxen Sodium+domperidone for an extended period.
Patients Concern
Disease/Condition Glossary
Migraine: Migraine is a condition characterised by intense headaches. It also causes nausea, vomiting, sensitivity to light and sound and difficulty speaking. Bright lights, strong smells, certain foods, loud sounds, stress and hormonal changes act as triggers for migraine. These triggers lead to acute attacks. Acute migraine attacks result in throbbing headaches and pain in the eyes, face or neck.
Pain: Pain is a widely used term to describe unpleasant feelings or discomfort. It ranges from mild to severe. The severity of the pain depends on the underlying condition.
Rheumatoid arthritis: Rheumatoid arthritis is an autoimmune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities and loss of joint function.
Osteoarthritis: Osteoarthritis is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation and tenderness.
Dysmenorrhea: Menstrual cramps, also known as dysmenorrhea, are characterised by cramps and pain during menstruation due to heavy flow. Pain, cramps and discomfort during periods are normal. However, excessive pain during periods is not normal and requires medication. Symptoms of dysmenorrhea include intense throbbing pain in the lower abdomen, dull, continuous ache, pain in the lower back and thighs, nausea, headache, and dizziness. The pain usually starts 1-3days before the period, peaks one day before the period starts and subsides 2-3days after the onset of the period.
FAQs
Naproxen Sodium+domperidone is primarily used in the treatment of migraine headaches. It can also treat pain associated with rheumatoid arthritis, arthritis, gout, dysmenorrhea (menstrual pain), and various muscle and bone disorders, including back pain, sprains, and strains.
Naproxen Sodium+domperidone is a medication combination of Naproxen Sodium and Domperidone. Naproxen is a nonsteroidal anti-inflammatory medication (NSAID). It alleviates joint and muscular pain and swelling (inflammation). Domperidone, on the other hand, is an anti-sickness medication. It assists you in stopping the feeling of being unwell (nausea or vomiting).
Yes, Naproxen Sodium+domperidone may cause drowsiness. Therefore, it is advisable not to drive or operate heavy machinery while taking Naproxen Sodium+domperidone.
Naproxen Sodium+domperidone cannot permanently cure migraine. It can provide relief from pain and headache.
Naproxen Sodium+domperidone on prolonged or frequent use can cause liver or kidney problems. Therefore, it should be used only for a duration as prescribed by the doctor.
Dry mouth may be caused by Domperidone in Naproxen Sodium+domperidone. Chew a sugar-free sweet or sugar-free gum.
Naproxen Sodium+domperidone is usually not advised if you have stomach ulcers, bleeding in the stomach or intestines, or a hole in your stomach. If you have any concerns, please address them with your doctor.
Naproxen Sodium+domperidone should be taken with or just after a meal or snack.
The most common side effects of Naproxen Sodium+domperidone are dry mouth, confusion, headache, ringing in the ears, changes in vision, tiredness, dizziness, drowsiness, and rashes. These side effects are usually mild and typically resolve on their own. However, please reach out to your doctor if the side effects persist or worsen.
Naproxen Sodium+domperidone is a combination medicine used in the treatment of migraine headache and also helps reduce pain associated with rheumatoid arthritis, arthritis, gout, dysmenorrhea (menstrual pain), and muscle and bone disorders, such as back pain, sprains, and strains.
Do not stop using Naproxen Sodium+domperidone even if you feel better until the doctor’s advised course is finished. Your symptoms may improve, but the condition may not be cured completely.
It's crucial to consult with a healthcare professional before starting Domperidone-Naproxen 500 tablets, especially if you have any underlying health conditions. They can assess your individual situation and determine if the benefits outweigh the risks.
Naproxen Sodium+domperidone on prolonged or frequent use can cause liver or kidney problems. Therefore, it should be used only for a duration as prescribed by the doctor. It is recommended to check the liver profile regularly if necessary.
No, taking a higher dose than the suggested dose may not be more effective; rather, it may enhance the chances of having severe side effects and toxicity.
Store in a cool, dry place, away from sunlight. Keep out of sight and reach of children.
