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Ofloxacin+flavoxate

About Ofloxacin+flavoxate

Ofloxacin+flavoxate is used to treat bacterial infections of the urinary tract (kidney and bladder). Ofloxacin+flavoxate helps relieve symptoms which may occur due to the infection, such as painful urination, inability to control urine flow, and excessive urination at night. Urinary tract infections are caused by microbes such as bacteria and can affect the kidneys, bladder, and the tubes that run between them.

Ofloxacin+flavoxate is a combination of two drugs: Ofloxacin (quinolone antibiotic) and Flavoxate (anti-spasmodic). Ofloxacin prevents the bacteria from repairing and reproducing themselves, thereby killing the bacteria. Flavoxate relaxes the muscles of the urinary bladder, thereby helps in preventing frequent urination, and excessive or uncontrolled urination. 
 
In some cases, you may experience certain common side effects, such as nausea, vomiting, stomach upset, dizziness, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Ofloxacin+flavoxate contains ofloxacin, which might increase the chances of developing tendinitis (swelling of a fibrous tissue that connects a bone to a muscle) or having a tendon rupture (tearing of a fibrous tissue that connects a bone to a muscle). Consult your doctor before taking Ofloxacin+flavoxate if you are pregnant or breast-feeding. Ofloxacin+flavoxate may cause dizziness, so drive with caution. Ofloxacin+flavoxate should not be given to children as safety and efficacy have not been established. Avoid or limit the intake of alcohol while taking Ofloxacin+flavoxate as it could lead to increased dizziness.

Uses of Ofloxacin+flavoxate

Ofloxacin+flavoxate is used in the treatment of urinary tract infections. The detailed uses of Ofloxacin+flavoxate are as follows:
• Treatment of Urinary Tract Infections: Ofloxacin+flavoxate helps in treating infections in the urinary tract caused by bacteria, alleviating symptoms such as pain and frequent urination.
• Prophylactic Use: Ofloxacin+flavoxate can be used as a preventive measure for individuals prone to recurrent urinary tract infections, ensuring reduced occurrence of infections.
• Post-Surgical Use: Patients undergoing urological surgeries may be prescribed Ofloxacin+flavoxate to prevent infections during recovery.
• Management of Pyelonephritis: Ofloxacin+flavoxate can be effective in treating more severe kidney infections known as pyelonephritis that arise from untreated bladder infections.
• Support for Complicated UTIs: In cases of complicated urinary tract infections, Ofloxacin+flavoxate may be utilised to aid in addressing the infection when other antibiotics may not be effective.

Medicinal Benefits

Ofloxacin+flavoxate belongs to the group of medicines called antibiotics used to treat bacterial infections of the urinary tract (kidney and bladder). Ofloxacin+flavoxate helps to relieve symptoms which may occur due to the infection, such as painful urination, inability to control urine flow, and excessive urination at night. Ofloxacin+flavoxate is a combination of two drugs: Ofloxacin (quinolone antibiotic) and Flavoxate (anti-spasmodic). Ofloxacin prevents the bacteria from repairing and reproducing themselves, thus killing the bacteria. Flavoxate relaxes the muscles of the urinary bladder, thereby helps in preventing frequent urination, and excessive or uncontrolled urination.

Directions for Use

• Ofloxacin+flavoxate can be taken with or without food as advised by your doctor. • Follow your doctor's instructions on the dosage and timing of this medication. • Swallow Ofloxacin+flavoxate as a whole with a glass of water. • Do not crush, break, or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ofloxacin+flavoxate

  • Nausea
  • Vomiting
  • Stomach upset
  • Dizziness
  • Headache

Drug Warnings

Do not take Ofloxacin+flavoxate if you are allergic to any of its contents; if you have gastrointestinal bleeding, obstruction in food passage, muscular inability to swallow, urinary retention, glaucoma, seizures or muscle weakness. Ofloxacin+flavoxate contains ofloxacin which might increase the chances of developing tendinitis (swelling of a fibrous tissue that connects a bone to a muscle) or having a tendon rupture (tearing of a fibrous tissue that connects a bone to a muscle). Talk to your doctor before taking Ofloxacin+flavoxate if you have mental illness, nervous, heart, kidney or liver problems. Consult your doctor before taking Ofloxacin+flavoxate if you are pregnant or breast-feeding. Ofloxacin+flavoxate may cause dizziness, so drive only if you are alert. Ofloxacin+flavoxate should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with Ofloxacin+flavoxate as it could lead to increased dizziness.

Drug Interactions

Drug-Drug Interactions: Ofloxacin+flavoxate may interact with anticonvulsant (topiramate, valproic acid), antihistamine (diphenhydramine, chlorpheniramine, cetirizine), anti-anxiety (alprazolam and duloxetine), pain killers (aspirin, ibuprofen, acetaminophen), anti-spasmodic (oxybutynin), anti-depressant (fluoxetine), antibiotic (azithromycin, sulfamethoxazole, trimethoprim, erythromycin), corticosteroid (dexamethasone), diuretic (furosemide).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have urinary or gastrointestinal obstruction, glaucoma, colitis (inflammation of the colon), CNS disorders, myasthenia gravis (neuromuscular disease), peripheral neuropathy (nerve pain), tendonitis (inflammation of tendons), or heart problems.

Drug-Drug Interactions Checker List:

  • TOPIRAMATE
  • VALPROIC ACID
  • DIPHENHYDRAMINE
  • CHLORPHENIRAMINE
  • CETIRIZINE
  • ALPRAZOLAM
  • DULOXETINE
  • ASPIRIN
  • IBUPROFEN
  • ACETAMINOPHEN
  • OXYBUTYNIN
  • FLUOXETINE
  • AZITHROMYCIN
  • SULPHAMETHOXAZOLE+TRIMETHOPRIM
  • ERYTHROMYCIN
  • DEXAMETHASONE
  • FUROSEMIDE
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      You are recommended to avoid alcohol consumption while taking Ofloxacin+flavoxate. Alcohol intake, along with Ofloxacin+flavoxate, may cause increased dizziness.

    • Safety Warning

      Pregnancy

      caution

      Please consult your doctor if you have any concerns regarding this; your doctor will prescribe you Ofloxacin+flavoxate only if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      Please consult your doctor if you have any concerns regarding this; your doctor will decide whether breastfeeding mothers can take Ofloxacin+flavoxate or not.

    • Safety Warning

      Driving

      caution

      Ofloxacin+flavoxate may cause dizziness, do not drive or operate heavy machinery if you feel dizzy.

    • Safety Warning

      Liver

      caution

      Dose adjustment may be needed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

    • Safety Warning

      Kidney

      caution

      Dose adjustment may be needed. Please consult your doctor if you have kidney impairment or any concerns regarding this.

    • Safety Warning

      Children

      unsafe

      Ofloxacin+flavoxate should not be used by children, as the efficacy and safety have not been established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
    • Antibiotics can alter the useful bacteria in the stomach, which help indigestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
    • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.
    • Pelvic floor exercises would help treat bladder spasms.
    • Avoid foods like sugars, carbonated beverages, tea, citrus fruits, tomatoes, spicy foods, chocolate and tea. 
    • Drink 6-8 glasses of water every day.
    • Do not hold in the urine for longer periods.
    • Avoid drinking excess alcohol or caffeine.
    • Maintain a healthy weight, exercise regularly.

    Patients Concern

    Disease/Condition Glossary

    Urinary tract infections (UTI): UTI is an infection in any part of the urinary system- the kidneys, bladder or urethra. A bladder infection may cause an increased urge to urinate, pelvic pain, pain during urination, and blood in the urine. A kidney infection may cause tenderness and pain in the back, fever, chills, nausea, and vomiting. The causes of UTI include a weak immune system, kidney stones, enlarged prostate, prolonged use of urinary catheters, diabetes, poor bathroom hygiene, sexual activity and age. Urinary tract infections are contagious and can spread to other body parts easily. Early diagnosis and treatment can help in preventing further complications.

    FAQs

    Ofloxacin+flavoxate belongs to the group of medicines called antibiotics used to treat bacterial infections of the urinary tract (kidney and bladder). Ofloxacin+flavoxate helps relieve symptoms which may occur due to the infection, such as painful urination, inability to control urine flow, and excessive urination at night.

    Ofloxacin+flavoxate is a combination of two drugs, namely: Ofloxacin (quinolone antibiotic) and Flavoxate (anti-spasmodic). Ofloxacin prevents the bacteria from repairing and reproducing themselves, thereby kills the bacteria. Flavoxate relaxes the muscles of the urinary bladder, thereby helps in preventing frequent urination, excessive or uncontrolled urination.

    Ofloxacin+flavoxate contains ofloxacin which may cause photosensitivity (sensitivity to sunlight) in some people. Always wear sunscreen before going out and avoid prolonged exposure to sunlight.

    Ofloxacin+flavoxate may cause stomach upset as a side-effect. To avoid this, take Ofloxacin+flavoxate with food.

    Avoid drinking tea, coffee (caffeinated drinks), and carbonated beverages as they might increase the urine flow and cause worsening of symptoms.

    Ofloxacin+flavoxate contains an antibiotic that kills or prevents bacterial growth, so in case some good intestinal bacteria which aid in digestion might also get killed, due to this diarrhoea might occur as a side-effect of Ofloxacin+flavoxate. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, stop taking Ofloxacin+flavoxate and consult your doctor. Do not take anti-diarrheal medicine on your own.

    To treat your condition effectually, do not stop taking Ofloxacin+flavoxate on your own. Continue taking Ofloxacin+flavoxate for as long as it has been prescribed to you.

    Choosing the right antibiotic for a UTI depends on several factors, including the severity of the infection, the type of bacteria, and the patient's medical history. A healthcare professional will consider these factors to decide the best treatment.

    The dosage and duration of treatment depend on the severity of the infection and your medical history. Generally, it is taken once or twice a day, as your doctor advises. However, follow your doctor's instructions regarding the dosage and duration of Ofloxacin+flavoxate. Do not self-medicate or adjust the dosage without consulting your doctor.

    Yes, the use of Ofloxacin+flavoxate can cause nausea and vomiting in some individuals. If you experience these symptoms, there are ways to alleviate them. Taking Ofloxacin+flavoxate with food, milk, or antacids can help minimize discomfort. Additionally, opting for lighter meals can also reduce nausea and vomiting. However, if these symptoms persist or worsen, it is essential to consult your doctor for further guidance and support.

    To store Ofloxacin+flavoxate properly, store it in a cool and dry place at a temperature not exceeding 30°C (86°F), away from direct sunlight and moisture. Additionally, it must be kept out of reach of children to maintain safety and prevent accidental ingestion.

    If you miss a dose of Ofloxacin+flavoxate, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed dose.

    The common side effects of Ofloxacin+flavoxate are nausea, vomiting, stomach upset, dizziness, and headache. Please consult your doctor if any of these side effects persist or worsen.

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    Ofloxacin+flavoxate

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