Ofloxacin+metronidazole
About Ofloxacin+metronidazole
Ofloxacin+metronidazole is an antibiotic medicine used to treat bacterial infections in children. It is used in treating infections of the skin, throat, ear, and lungs caused by bacteria. It is also used in the treatment of dysentery (bloody stools) caused by amoeba. A bacterial infection occurs when harmful bacteria enter and grow in the body. This bacteria can infect any part of the body and multiply very quickly. Amoebic dysentery can be caused due to Entamoeba histolytica, Giardia lamblia, or Clostridium difficile.
Ofloxacin+metronidazole is a combination medicine containing Ofloxacin (fluoroquinolone) and Metronidazole (antimicrobials). Ofloxacin works by inhibiting the repair of the bacterial cell wall (a protective covering) and causing damage to the bacterial cell wall. This eventually leads to the death of the bacterial cell and thus prevents the growth of bacterial infections. Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA.
Ofloxacin+metronidazole may cause certain side effects in your child such as indigestion, diarrhea, nausea, and stomach pain. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your paediatrician. Ofloxacin+metronidazole should be given as advised by your paediatrician. Do not give more than the prescribed dose of Ofloxacin+metronidazole to the child. Generally, the dose of the medicine will be decided by your paediatrician depending upon the type and severity of the infection.
Ofloxacin+metronidazole is intended for pediatric use only. Avoid giving Ofloxacin+metronidazole to your child if she/he is allergic to antibiotics. Keep your doctor informed about your child’s health condition including his current medications and medical history to rule out any side effects/interactions. Before administration, let your paediatrician know if your child has lung disease, muscle weakness, liver, and kidney disease.
Uses of Ofloxacin+metronidazole
• Tooth abscesses and gum infections: Ofloxacin+metronidazole is used in the treatment of tooth abscesses and gum infections.
• Treatment of Gastrointestinal infections: Ofloxacin+metronidazole is used in the treatment of gastrointestinal infections such as diarrhea and dysentery.
• Treatment of bacterial and parasitic infections: Ofloxacin+metronidazole is used in the treatment of various infections like lung infections, urinary tract infections and genital tract infections.
Medicinal Benefits
Ofloxacin+metronidazole contains Ofloxacin and Metronidazole (antimicrobials). Both these drugs are broad-spectrum antibiotics that act against aerobic (grow in the presence of oxygen) and anaerobic (grow in the absence of oxygen) bacteria. Ofloxacin+metronidazole is used in the treatment of several bacterial infections and amoebic dysentry in children. Ofloxacin works by inhibiting the repair of the bacterial cell wall (a protective covering) and causing damage to the bacterial cell wall. This eventually leads to the death of the bacterial cell and thus prevents the growth of bacterial infections. Metronidazole works by damaging the DNA. This kills parasites and anaerobic bacteria that are responsible for causing infections.
Directions for Use
- Ofloxacin+metronidazole can be administered with or without food as directed by the doctor.
- Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
- Administer the prescribed dose to the child using the measuring cup/dosing syringe.
- Shake well before use.
Storage
Side Effects of Ofloxacin+metronidazole
- Nausea
- Diarrhea
- Stomach upset
- Indigestion
- Vomiting
Drug Warnings
Avoid giving Ofloxacin+metronidazole to your child if she/he is allergic to antibiotics. Keep your doctor informed about your child’s health condition including his current medications and medical history to rule out any side effects/interactions. Before administration, let your paediatrician know if your child has lung disease, muscle weakness, liver, and kidney disease. Dairy products should be avoided along with Ofloxacin+metronidazole.
Drug Interactions
Drug-Drug Interactions: Ofloxacin+metronidazole may interact with caffeine-containing medications, antacids, etc. Give Ofloxacin+metronidazole either 2 hours before or 2 hours after taking an antacid, multivitamin, or other product that has calcium/magnesium/aluminium/iron/zinc,
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: Inform your doctor before administering Ofloxacin+metronidazole if your child has any history of lung disease, kidney or liver disease.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
not applicable-
Pregnancy
not applicable-
Breast Feeding
not applicable-
Driving
not applicable-
Liver
cautionPlease consult your doctor if your child has a liver impairment or if you have any concerns regarding this.
Kidney
cautionPlease consult your doctor if your child has a kidney impairment or if you have any concerns regarding this.
Children
safe if prescribedOfloxacin+metronidazole is safe for children if prescribed by the doctor. The dose of the medicine will be decided by your paediatrician. Do not give more than the recommended dose to your child.
Habit Forming
Diet & Lifestyle Advise
- Include more fiber-enriched food in your child’s diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth.
- Fiber foods may help restore healthy gut bacteria after a course of antibiotics.
- Avoid giving too much calcium, or iron-enriched foods, as it might affect the working of Ofloxacin+metronidazole.
- Make your child drink more fluids to avoid dehydration.
- Do not make your child drink or eat a lot of caffeine-containing products such as cola, or chocolate.
Patients Concern
Disease/Condition Glossary
Bacterial infection: A bacterial infection occurs when harmful bacteria enter, grow, and infect the body. It can infect any part of the body and multiply very quickly. These infections vary from minor illnesses to severe brain infections like meningitis and encephalitis. When your child gets infected with these germs, they can experience generalized symptoms, like fevers, chills, and fatigue. Children with a weak immune system are more prone to infections.
Amoebic dysentery: It is an intestinal infection caused by the protozoal parasite named Entamoeba histolytica. Symptoms may include fever, chills, bloody diarrhoea, and abdominal discomfort. It can also cause constipation in some children.
FAQs
Ofloxacin+metronidazole is used to treat Bacterial Infections and Amoebic dysentry.
Ofloxacin+metronidazole is a combination medicine containing Ofloxacin (fluoroquinolone) and Metronidazole. Ofloxacin works by inhibiting the repair of the bacterial cell wall (a protective covering) and causing damage to the bacterial cell wall. This e Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA.
No. As it is an antibiotic, it is advised to complete the entire treatment course of your child as prescribed. If the treatment is stopped abruptly, there may be drug resistance.
Ofloxacin+metronidazole can cause diarrhea in children. Ofloxacin+metronidazole is an antibiotic that kills toxic bacteria, but it can also affect the useful bacteria in your intestine or stomach and lead to diarrhea. If your child experience diarrhea that is watery or bloody, call your doctor. Do not use anti-diarrheal medicine unless your paediatrician suggests it.
Let the doctor know if the child has liver problems, blood issues, a low white blood cell count (leukopenia), or nervous system conditions (such as convulsions). Taking Ofloxacin+metronidazole may also increase the risk of developing tendinitis (swelling of the tissue that connects bone to muscle) or tendon rupture. Dairy products should be avoided while using Ofloxacin+metronidazole, and you should limit exposure to sunlight, as it may increase the risk of phototoxicity or photosensitivity.
Ofloxacin+metronidazole can be useful in treating loose motions if the cause is a bacterial or parasitic infection. However, it is not recommended for all cases of diarrhoea, as it may not be effective for viral infections or non-infectious causes. Please consult your doctor for proper diagnosis and treatment.
If your child develops a rash after taking Ofloxacin+metronidazole, it could be a sign of an allergic reaction or a side effect. Discontinue the medication right away and contact your doctor to discuss what to do next and get the right treatment.
Yes, Ofloxacin+metronidazole is an antibiotic that combines two medicines: ofloxacin and metronidazole. Ofloxacin targets bacterial DNA replication, while metronidazole is effective against anaerobic bacteria and certain parasites. Both are bactericidal in nature, and collectively they help treat the infection effectively.
If you accidentally give an excess dose of Ofloxacin+metronidazole, monitor for potential side effects such as nausea, vomiting, stomach upset, loss of appetite, dry mouth, and a metallic taste. Contact your doctor immediately, as taking too much of the antibiotic may lead to adverse reactions.
If your child shows no improvement even after completing the prescribed course of Ofloxacin+metronidazole, please consult your doctor. Also, inform the doctor if the symptoms are getting worse while using Ofloxacin+metronidazole.
To prevent any interactions, it is advised to consult the doctor before using other medicines with Ofloxacin+metronidazole. Inform the doctor if the child is taking anti-arrhythmics (quinidine, hydroquinidine, disopyramide, amiodarone, sotalol, dofetilide, ibutilide), tricyclic antidepressants, (clomipramine, amitriptyline), antipsychotics, or antimicrobials (erythromycin, clarithromycin, azithromycin).
Though Ofloxacin+metronidazole may not interact with vaccines, it is advised to consult the doctor before receiving vaccination. Let the doctor know if your child is due to undergo vaccination while on treatment with Ofloxacin+metronidazole.
Before giving Ofloxacin+metronidazole to your child, tell the doctor if your child has any allergies, especially to any of its ingredients, or to other antibacterial or anti-amoebic medicines. You should inform the doctor if your child has any existing medical conditions, such as liver or kidney problems, low white blood cell count (leukopenia), or muscle spasms (convulsions). Also, let the doctor know if your child is taking any other medications to prevent potential interactions.
Ofloxacin+metronidazole contains metronidazole which might cause reddish-brown discolouration of urine as a side effect. It is usually harmless, and the condition will subside once treatment is completed. However, consult the doctor if you have any concerns or notice dark urine or blood in urine.
It is best to consult your doctor before giving Ofloxacin+metronidazole along with cough & cold medicines. Ofloxacin+metronidazole is typically used to treat bacterial infections, but it does not work against viral infections like the common cold.
The common side effects of Ofloxacin+metronidazole include nausea, vomiting, stomach pain, headache, and dizziness. If these side effects persist or worsen, please consult your doctor.
If you forget to give Ofloxacin+metronidazole to your child, give the missed dose as soon as you remember, unless it is almost time for the next dose. If that is the case, skip the missed dose and give the next dose at the usual time. Never give two doses at once to make up for a missed dose.
Yes, Ofloxacin+metronidazole is a broad-spectrum antibiotic that can treat a variety of infections in different parts of the body. It is effective against infections in areas such as the gastrointestinal tract, lungs, blood, heart, skin, bones, joints, and nervous system.
