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Pantoprazole+cinitapride

About Pantoprazole+cinitapride

Pantoprazole+cinitapride is used to treat gastro-oesophageal reflux disease (GERD), indigestion, duodenal ulcers, erosive oesophagitis (acid-related damage to the lining of the oesophagus), infections caused by Helicobacter pylori when given along with an antibiotic, and Zollinger-Ellison syndrome.

Pantoprazole+cinitapride contains Pantoprazole and Cinitapride. Pantoprazole works by reducing the production of stomach acid. Cinitapride prevents the backflow of food and acid from the stomach into the mouth. Together, Pantoprazole+cinitapride helps treat acidity-related conditions.

In some cases, Pantoprazole+cinitapride may cause side effects, such as headache, flatulence, stomach pain, constipation, and diarrhoea. Most of these side effects do not require medical attention and resolve over time. However, talk to your doctor if the side effects persist or worsen.

Do not take Pantoprazole+cinitapride if you are allergic to any of its components. Consult your doctor if you are pregnant or breastfeeding. Pantoprazole+cinitapride may cause dizziness, so drive only if you are alert. Keep your doctor informed about your medications and health conditions to rule out any interactions.

Uses of Pantoprazole+cinitapride

Pantoprazole+cinitapride is used to treat acid-related stomach and oesophageal disorders. The detailed uses of Pantoprazole+cinitapride are as follows: • Gastro-oesophageal reflux disease (GERD): Pantoprazole+cinitapride reduces heartburn and prevents acid from flowing back into the oesophagus. • Indigestion: Pantoprazole+cinitapride relieves discomfort, bloating, and pain due to excessive stomach acid production. • Duodenal ulcers: Pantoprazole+cinitapride promotes healing of ulcers in the upper small intestine by reducing acid production. • Erosive oesophagitis: Pantoprazole+cinitapride protects the oesophageal lining from acid-related injury. • Helicobacter pylori infection: Pantoprazole+cinitapride aids in the eradication of H. pylori bacteria and the healing of ulcers when combined with antibiotics. • Zollinger-Ellison syndrome: Pantoprazole+cinitapride controls excessive stomach acid production in ZES.

Medicinal Benefits

  • Pantoprazole+cinitapride reduces acid production and prevents acid backflow, offering relief from heartburn and regurgitation.
  • It enhances gastrointestinal motility and speeds up gastric emptying, improving digestion and reducing bloating, fullness, and discomfort.
  • It lowers stomach acid levels, allowing ulcerated areas in the stomach and duodenum to heal effectively.
  • Pantoprazole+cinitapride protects and helps heal the lining of the oesophagus that has been damaged by stomach acid.
  • When used with antibiotics, it aids in the treatment of Helicobacter pylori infections, which cause peptic ulcers.
  • It treats Zollinger-Ellison Syndrome by controlling excessive acid secretion caused by gastrin-producing tumours.
  • Pantoprazole+cinitapride is beneficial in patients with delayed gastric emptying or other motility disorders, helping reduce symptoms like bloating and early satiety.

Directions for Use

  • Take Pantoprazole+cinitapride 30-60 minutes before food as advised by a doctor.
  • Follow your doctor’s recommendations on the dosage and timing of this medication to achieve optimal results.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Pantoprazole+cinitapride

  • Headache
  • Flatulence
  • Stomach pain
  • Constipation
  • Diarrhoea

Drug Warnings

  • Do not take Pantoprazole+cinitapride if you are allergic to any of its components.
  • Inform your doctor before taking Pantoprazole+cinitapride if you have severe liver or kidney problems or if you are due to have a Chromogranin A test.
  • Consult your doctor if you experience unexplained weight loss, stomach pain, indigestion, vomit food or blood, or if you pass black stools.
  • On long-term treatment, Pantoprazole+cinitapride may cause osteoporosis and hypomagnesemia (low levels of magnesium) and may reduce the absorption of vitamin B12.
  • Consult your doctor if you are pregnant or breastfeeding.
  • Pantoprazole+cinitapride may cause dizziness, so drive only if you are alert.
  • This medicine should not be given to children as safety has not been established.
  • Let your doctor know if you are taking any other medicines, including supplements and herbal products.

Drug Interactions

Drug-Drug Interactions: Inform your doctor if you are taking pain killers (aspirin, naproxen), antidepressant (duloxetine), hormone (levothyroxine), statins (atorvastatin), blood thinner (clopidogrel), vitamin (cyanocobalamin), antipsychotic (phenothiazine), cardiac glycoside (digoxin), medicines used to treat schizophrenia, an overactive bladder, COPD or opioid analgesics (used to relieve pain).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Inform your doctor if you have gastrointestinal bleeding, mechanical obstruction or perforation, Clostridium difficile-associated diarrhoea (CDAD), liver disease, bone fractures, or hypomagnesemia (low magnesium levels).

Drug-Drug Interactions Checker List:

  • ASPIRIN
  • NAPROXEN
  • DULOXETINE
  • LEVOTHYROXINE SODIUM
  • ATORVASTATIN
  • CLOPIDOGREL
  • CYANOCOBALAMIN
  • PHENOTHIAZINE
  • DIGOXIN
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Avoid consumption of alcohol while taking Pantoprazole+cinitapride. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

    • Safety Warning

      Pregnancy

      caution

      Consult your doctor before taking Pantoprazole+cinitapride if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      Consult your doctor before taking Pantoprazole+cinitapride if you are breastfeeding; your doctor will decide whether breastfeeding mothers can take Pantoprazole+cinitapride or not.

    • Safety Warning

      Driving

      caution

      Pantoprazole+cinitapride may cause dizziness. Do not drive or operate machinery unless you are alert.

    • Safety Warning

      Liver

      caution

      Dose adjustment may be needed. Consult your doctor before taking Pantoprazole+cinitapride if you have a liver impairment or any concerns regarding this.

    • Safety Warning

      Kidney

      caution

      Dose adjustment may be needed. Consult your doctor before taking Pantoprazole+cinitapride if you have kidney impairment or any concerns regarding this.

    • Safety Warning

      Children

      unsafe

      Pantoprazole+cinitapride should not be given to children as safety and effectiveness were not established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Eat smaller meals more often.
    • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
    • Maintain a healthy weight through regular exercise.
    • Avoid lying down after eating to prevent acid reflux.
    • Avoid tight-fitting clothes as they might increase the pressure on the abdomen, leading to acid reflux.
    • Practice relaxation techniques and avoid stress by doing yoga or meditation.
    • Avoid foods such as high-fat foods, spicy foods, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea, and soda.
    • Avoid sitting for long periods, as it may trigger acidity. Take a 5-minute break every hour by brisk walking or stretching.

    Special Advise

    • Inform your doctor before taking Pantoprazole+cinitapride if you are due to have a Chromogranin A test.
    • Regular monitoring of magnesium and vitamin B12 levels is advised if you are on long-term treatment with Pantoprazole+cinitapride.
    • Your doctor may recommend calcium and vitamin supplements if you are on long-term treatment with Pantoprazole+cinitapride.

    Patients Concern

    Disease/Condition Glossary

    Gastroesophageal reflux disease (GERD): Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, sour or bitter taste in the mouth, and difficulty swallowing.

    Peptic ulcers: Peptic ulcers are sores that develop on the lining of the stomach and intestine due to erosion of the stomach's protective lining. Symptoms include nausea, changes in appetite, bloody or dark stools, unexplained weight loss, vomiting, and indigestion.

    Indigestion: Indigestion is the feeling of fullness. It occurs due to slow gastric emptying. Symptoms include stomach pain, bloating, heartburn, nausea and vomiting.

    Zollinger-Ellison syndrome: It is a rare condition in which a gastrin-secreting tumour of the pancreas causes excessive acid production, leading to peptic ulcers.

    FAQs

    Pantoprazole+cinitapride is used to treat gastro-oesophageal reflux disease (GERD), indigestion, duodenal ulcers, erosive oesophagitis (acid-related damage to the lining of the oesophagus), infections caused by Helicobacter pylori when given along with an antibiotic, and Zollinger-Ellison syndrome.

    Pantoprazole+cinitapride contains Pantoprazole and Cinitapride. Pantoprazole works by blocking the action of an enzyme called the gastric proton pump, which is responsible for the production of stomach acid. Cinitapride increases the pressure of the inferior oesophageal sphincter, thereby preventing the back-flow of food and acid from the stomach into the mouth. Together, Pantoprazole+cinitapride helps in preventing acid reflux, thereby providing relief from acidity and heartburn.

    Diarrhoea might be a side-effect of Pantoprazole+cinitapride. Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

    Avoid lying down immediately after meals to prevent symptoms of acid reflux. After having a meal, try 10-15 minutes of brisk walking, especially after dinner. Raise the head of the bed 10-20 cm by putting a pillow so that the head and chest are above the waist. This helps prevent acid reflux.

    Pantoprazole+cinitapride contains pantoprazole, which might increase the risk of bone fracture in the hip, spine, or wrist due to the decreased magnesium level in bones. This mainly occurs in people taking higher doses of Pantoprazole+cinitapride for longer durations. Inform your doctor before taking Pantoprazole+cinitapride if you have osteoporosis or if you are taking corticosteroids.

    Dry mouth could be a side effect of Pantoprazole+cinitapride. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevent dry mouth.

    Depending on your medical condition, you are advised to take Pantoprazole+cinitapride for as long as your doctor has prescribed it. If you face any difficulty while taking it, stop using it and consult the doctor.

    No, Pantoprazole+cinitapride is not an antibiotic medication. It is an antacid medication.

    Yes, it can be taken on an empty stomach, preferably 30-60 minutes before food.

    Pantoprazole+cinitapride contains Cinitapride (gastroprokinetic agent) and Pantoprazole (proton pump inhibitor).

    Common side effects of Pantoprazole+cinitapride may include headache, flatulence, stomach pain, constipation, and diarrhoea. Consult your doctor if any of the side effects persist or worsen.

    No, it is used to treat acidity-related conditions and does not treat loose motions. Consult your doctor if you have diarrhoea.

    Available Medicines for

    Pantoprazole+cinitapride

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