Phospholipid
About Phospholipid
Phospholipid belongs to the class of lung surfactants. It is used to treat Neonatal Respiratory Distress Syndrome (NRDS/Hyaline Membrane Disease). Neonatal Respiratory Distress Syndrome (NRDS/Hyaline Membrane Disease) is a condition that occurs when a baby's lungs are not fully developed and cannot provide enough oxygen, causing breathing difficulties. It usually affects premature babies.
It contains phospholipid (bovine lipid). Phospholipid works by providing the (phospholipid) bovine lipid extract surfactant to the lungs of newborn babies with NRDS. The surfactant spreads through the lungs, allowing the lungs to expand properly and oxygen to enter the blood more easily. This will lower the baby’s need for extra oxygen and make breathing easier.
In some cases, this medicine may cause side effects such as patent ductus arteriosus, decreased post-dose pulmonary function values, intraventricular hemorrhage of all grades, infection throughout the body (sepsis), retinopathy of prematurity, bradycardia, and severe intraventricular hemorrhage. However, after giving Phospholipid, the doctor will closely monitor the baby's health status. If any adverse effects occur, your doctor will take the necessary action for your baby.
Inform your doctor about the baby’s birth history (like age, weight, and any other complications during delivery) and all the medications and pre-medical conditions of the premature baby. Phospholipid is not given at the same time if the infant has active pulmonary hemorrhage (lungs may be bleeding).
Uses of Phospholipid
• Respiratory Distress Syndrome Treatment: Phospholipid plays a critical role in treating Respiratory Distress Syndrome (RDS) in newborns by replacing surfactant, a substance that helps keep lungs open, thereby improving lung function and breathing.
• Improvement of Lung Function: Phospholipid improves lung function by reducing surface tension in the alveoli, enabling better gas exchange and easier breathing for newborns with RDS.
• Support in Premature Infants: Phospholipid provides crucial support to premature infants at risk of RDS, helping prevent complications associated with underdeveloped lungs and surfactant deficiency.
• Facilitation of Ventilation: Phospholipid facilitates ventilation by improving lung compliance, allowing mechanical ventilators to deliver effective breaths more easily, and supporting better oxygenation and lung function in infants.
• Reduction of Oxygen Requirements: Phospholipid helps to reduce the need for supplemental oxygen in infants with RDS by improving lung function and oxygenation, thereby supporting their respiratory health.
Medicinal Benefits
Phospholipid is a natural phospholipid, bovine lipid extract surfactant, derived from a natural substance essential for effective breathing. It is used to treat Neonatal Respiratory Distress Syndrome (NRDS/Hyaline Membrane Disease) in premature babies. The bovine lipid extract surfactant contains natural fats and proteins. In babies who lack sufficient surfactant, this medication spreads through the lungs, helping them expand properly and allowing oxygen to enter the blood more easily. As a result, it reduces the baby's need for extra oxygen and makes breathing easier.
Directions for Use
• Follow your doctor's instructions on the dosage and timing of this medication. • Phospholipid is administered by the doctor or healthcare professional. • Do not self-administer.
Storage
Side Effects of Phospholipid
- Patent ductus arteriosus
- Decreased post-dose pulmonary function values
- Intraventricular hemorrhage of all grades
- Infection throughout the body(sepsis)
- Retinopathy of prematurity
- Bradycardia
- Severe intraventricular hemorrhage
Drug Warnings
Phospholipid is not given at the same time if the infants with active pulmonary hemorrhage (lungs may be bleeding).
Drug Interactions
Drug-Drug Interactions: No interactions found.
Drug-Food Interactions: No interactions found.
Drug-Disease Interactions: Phospholipid is not administered in infants with active pulmonary haemorrhage (lung bleeding).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
not applicableNot applicable
Pregnancy
not applicableNot applicable
Breast Feeding
not applicableNot applicable
Driving
not applicableNot applicable
Liver
cautionIf your
Kidney
consult your doctorConsult your doctor If your baby has any kidney impairments before administering Phospholipid.
Children
safePhospholipid is given for the new born babies.
Habit Forming
Diet & Lifestyle Advise
- It is important to ensure proper breastfeeding for the baby. If breastfeeding is not possible, plan a method for giving the baby breast milk under the doctor's guidance.
- Keep the baby away from sick individuals and crowded places to reduce the risk of infections.
- Frequent check-ups with the paediatrician to monitor the baby's growth, development, and overall health.
- Create a calm and nurturing environment around the baby.
Patients Concern
Disease/Condition Glossary
NRDS: Neonatal Respiratory Distress Syndrome (NRDS/Hyaline Membrane Disease) occurs when a baby's lungs are not fully developed and cannot provide enough oxygen, causing breathing difficulties. It usually affects premature babies. It's also known as infant respiratory distress syndrome, hyaline membrane disease, or surfactant deficiency lung disease. The symptoms of NRDS are blue-coloured lips, fingers, and toes, rapid, shallow breathing, flaring nostrils, and a grunting sound when breathing.
FAQs
Phospholipid is used to treat Neonatal Respiratory Distress Syndrome (NRDS/Hyaline Membrane Disease) in premature babies.
Neonatal Respiratory Distress Syndrome (NRDS) typically affects babies who are born prematurely, but it can also occur in normally born babies born in conditions like if the mothers have diabetes, the baby is underweight, and the baby's lungs have not developed properly.
In some cases, Phospholipid may cause side effects such as patent ductus arteriosus, decreased post-dose pulmonary function values, intraventricular haemorrhage of all grades, infection throughout the body (sepsis), retinopathy of prematurity, bradycardia, severe intraventricular haemorrhage. However, after giving Phospholipid, the doctor will closely monitor the baby's health status. If any adverse effects occur, your doctor will take the necessary action for your baby.
Phospholipid works by providing the (phospholipid) bovine lipid extract surfactant to the lungs of newborn babies with NRDS; it spreads through the lungs, allowing the lungs to expand properly and oxygen to enter the blood more easily. This will lower the baby’s need for extra oxygen under pressure and make breathing easier.
Phospholipid is in the dosage form of suspension for intratracheal instillation.